Article thumbnail

Spontaneous Pneumothorax in an Allogeneic Cell Transplant Recipient with Invasive Pulmonary Aspergillosis and Antecedent RSV Pneumonitis.

By Liang-Piu Koh, Michelle Li-Mei Poon, John Kit-Chung Tam, Lynette Teo and Li-Yang Hsu


We report a case of invasive pulmonary aspergillosis (IPA) following respiratory syncytial virus infection in an allogeneic hematopoietic stem cell transplant (HSCT) recipient with chronic graft-versus-host disease. Delayed diagnosis of IPA resulted in the development of a pneumothorax, a rare consequence of fungal pneumonia. Respiratory virus infections are often harbingers of other infective organisms in HSCT recipients. More aggressive diagnostic investigations such as computed tomography scans of the thorax and bronchoscopy with bronchoalveolar lavage should be considered early in any HSCT patient presenting with respiratory virus pneumonia, particularly if atypical features are present or recovery is delayed

Topics: Case Reports
Publisher: Università Cattolica del Sacro Cuore
OAI identifier:
Provided by: PubMed Central

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.

Suggested articles


  1. Accuracy of BAL galactomannan in diagnosing invasive aspergillosis: a bivariate metaanalysis and systematic review.
  2. Chronic necrotizing pulmonary aspergillosis complicated by pneumothorax.
  3. (1996). Chronic necrotizing pulmonary aspergillosis complicated by pneumothorax. Nihon Kyobu Shikkan Gakkai Zasshi.
  4. Community-acquired respiratory syncytial virus and parainfluenza virus infections after hematopoietic stem cell transplantation: the Fred Hutchinson Cancer Research Center experience. Biol Blood Marrow Transplant. 2001;7 Suppl :11S-15S.
  5. Diagnostic bronchoscopy in hematology and oncology patients with acute respiratory failure: prospective multicenter data. Crit Care Med.
  6. Invasive aspergillosis in allogeneic stem cell transplant recipients: changes in epidemiology and risk factors.
  7. Pulmonary complications of solid organ and hematopoietic stem cell transplantation.
  8. Respiratory syncytial virus infection in the late bone marrow transplant period: report of three cases and review. Bone Marrow Transplant.