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p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype

By Adam Freund, Christopher K Patil and Judith Campisi

Abstract

Senescent cells were shown to secrete inflammatory cytokines and growth factors, depending upon activation of the DNA damage response. Campisi and colleagues now show that this also requires additional signalling via the stress-activated p38MAP kinase pathway

Topics: Article
Publisher: Nature Publishing Group
OAI identifier: oai:pubmedcentral.nih.gov:3102277
Provided by: PubMed Central
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