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Sense transcription through the S region is essential for immunoglobulin class switch recombination

By Dania Haddad, Zéliha Oruc, Nadine Puget, Nathalie Laviolette-Malirat, Magali Philippe, Claire Carrion, Marc Le Bert and Ahmed Amine Khamlichi

Abstract

Class switch recombination (CSR) is preceded by sense and antisense transcription of the switch (S) regions. While sense transcription of the S region is needed for CSR, antisense transcription is not essential

Topics: Article
Publisher: Nature Publishing Group
OAI identifier: oai:pubmedcentral.nih.gov:3102270
Provided by: PubMed Central
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