Article thumbnail

E. coli DNA replication in the absence of free β clamps

By Nathan A Tanner, Gökhan Tolun, Joseph J Loparo, Slobodan Jergic, Jack D Griffith, Nicholas E Dixon and Antoine M van Oijen


Single-molecule observations reveal that replicative DNA polymerases can surprisingly conduct lagging-strand synthesis with only a stoichiometric amount of sliding clamps, while they had so far been thought to hop from one clamp to another pre-assembled clamp on the next Okazaki fragment

Topics: Article
Publisher: Nature Publishing Group
OAI identifier:
Provided by: PubMed Central
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://www.pubmedcentral.nih.g... (external link)

  • To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.

    Suggested articles