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Estrogen-Initiated Transformation of Prostate Epithelium Derived from Normal Human Prostate Stem-Progenitor Cells

By Wen-Yang Hu, Guang-Bin Shi, Hung-Ming Lam, Dan-Ping Hu, Shuk-Mei Ho, Ikenna C. Madueke, Andre Kajdacsy-Balla and Gail S. Prins

Abstract

Normal human prostate progenitor cells are estrogen targets and estradiol, in an androgen-supported milieu, is capable of transformation and malignant progression of human prostate epithelium

Topics: Cancer-Oncogenes
Publisher: Endocrine Society
OAI identifier: oai:pubmedcentral.nih.gov:3100619
Provided by: PubMed Central
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