DNA methylation epigenotypes in breast cancer molecular subtypes
By Naiara G Bediaga, Amelia Acha-Sagredo, Isabel Guerra, Amparo Viguri, Carmen Albaina, Irune Ruiz Diaz, Ricardo Rezola, María Jesus Alberdi, Joaquín Dopazo, David Montaner, Mertxe de Renobales, Agustín F Fernández, John K Field, Mario F Fraga, Triantafillos Liloglou and Marian M de Pancorbo
(2003). Argani P: DNA methylation of RASSF1A, HIN-1, RAR-beta, cyclin D2 and twist in in situ and invasive lobular breast carcinoma.
(2006). Breast cancer DNA methylation profiles in cancer cells and tumor stroma: association with HER-2/neu status in primary breast cancer. Cancer Res
(2008). Clark SJ: Breast cancer epigenetics: normal human mammary epithelial cells as a model system. J Mol Med
(2007). Correlation between CpG methylation profiles and hormone receptor status in breast cancers. Breast Cancer Res
(2007). EA: MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype. Genome Biol
(2008). Epigenetic biomarkers for human cancer: the time is now. Crit Rev Oncol Hematol
(2001). Eystein Lønning P, Børresen-Dale AL: Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA
(2009). FA: DNA hypomethylation in the origin and pathogenesis of human diseases. Cell Mol Life Sci
(2008). Fan JB: Unraveling epigenetic regulation in embryonic stem cells. Cell Stem Cell
(2008). Global and regional CpG methylation in pheochromocytomas and abdominal paragangliomas: association to malignant behavior. Clin Cancer Res
(2002). GM: Genetic and epigenetic modification of mismatch repair genes hMSH2 and hMLH1 in sporadic breast cancer with microsatellite instability. Oncogene
(2001). Golani I: Controlling the false discovery rate in behavior genetics research. Behav Brain Res
(2001). GP: Hypermethylation of the cpG island of Ras association domain family 1A (RASSF1A), a putative tumor suppressor gene from the 3p21.3 locus, occurs in a large percentage of human breast cancers. Cancer Res
(2006). Henikoff S: The epigenetic progenitor origin of human cancer. Nat Rev Genet
(2001). Huang S: Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily. Cancer Res
(2006). JB: High-throughput DNA methylation profiling using universal bead arrays. Genome Res
(2006). JB: Human embryonic stem cells have a unique epigenetic signature. Genome Res
(2007). JP: Rare CpG island methylator phenotype in ulcerative colitis-associated neoplasias. Gastroenterology
(2009). K: Epigenetic patterns of embryonic and adult stem cells. Cell Cycle
(2001). K: HIN-1, a putative cytokine highly expressed in normal but not cancerous mammary epithelial cells. Proc Natl Acad Sci USA
(2009). KD: Unraveling breast cancer heterogeneity through transcriptomic and epigenomic analysis. Ann Surg Oncol
(2009). KT: Differentiation of lung adenocarcinoma, pleural mesothelioma, and nonmalignant pulmonary tissues using DNA methylation profiles. Cancer Res
(2010). LC: DNA methylation in embryonic stem cells.
(2008). Lera JM: Differences and molecular immunohistochemical parameters in the subtypes of infiltrating ductal breast cancer.
(2009). Liloglou T: Hypomethylation of retrotransposable elements correlates with genomic instability in nonsmall cell lung cancer.
(2009). Lindeman GJ: Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers. Nat Med
(2002). LW: E-cadherin promoter methylation can regulate its expression in invasive ductal breast cancer tissue in Chinese woman. Life Sci
(2005). M: p16(INK4a) promoter methylation and protein expression in breast fibroadenoma and carcinoma.
(2008). MF: Cancer genes hypermethylated in human embryonic stem cells. PLoS One
(2000). Molecular portraits of human breast tumours. Nature
(2005). Olopade OI: BRCA1 promoter methylation in sporadic breast cancer is associated with reduced BRCA1 copy number and chromosome 17 aneusomy. Cancer Res
(2007). Perou CM: The triple negative paradox: primary tumor chemosensitivity of breast cancer subtypes. Clin Cancer Res
(2009). PS: Supervised risk predictor of breast cancer based on intrinsic subtypes.
(2010). Ringnér M: Molecular subtypes of breast cancer are associated with characteristic DNA methylation patterns. Breast Cancer Res
(2004). S: PTEN promoter is methylated in a proportion of invasive breast cancers.
(2008). Sukumar S: Epigenomics and breast cancer. Pharmacogenomics
(2000). Sukumar S: High frequency of hypermethylation at the 14-3-3 sigma locus leads to gene silencing in breast cancer. Proc Natl Acad Sci USA
(2005). Towards the human cancer epigenome: a first draft of histone modifications. Cell Cycle
(2009). Ushijima T: Association between frequent CpG island methylation and HER2 amplification in human breast cancers. Carcinogenesis
(2003). Yu Y: Aberrant methylation and silencing of ARHI, an imprinted tumor suppressor gene in which the function is lost in breast cancers. Cancer Res
(2003). Yu Y: Reactivation of the silenced and imprinted alleles of ARHI is associated with increased histone H3 acetylation and decreased histone H3 lysine 9 methylation. Hum Mol Genet