Location of Repository

Activated IL-23/IL-17 pathway closely correlates with increased Foxp3 expression in livers of chronic hepatitis B patients

By Qinghong Wang, Yanhua Zheng, Zemin Huang, Yi Tian, Jijun Zhou, Qing Mao, Yuzhang Wu and Bing Ni
Topics: Research Article
Publisher: BioMed Central
OAI identifier: oai:pubmedcentral.nih.gov:3094328
Provided by: PubMed Central
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://www.pubmedcentral.nih.g... (external link)
  • Suggested articles

    Preview

    Citations

    1. (2008). A: Intrahepatic regulatory T cells are phenotypically distinct from their peripheral counterparts in chronic HBV patients. Clin Immunol
    2. (2004). A: Longitudinal analysis of CD8+ T cells specific for structural and nonstructural hepatitis B virus proteins in patients with chronic hepatitis B: implications for immunotherapy.
    3. (2009). Annunziato F: Properties and origin of human Th17 cells. Mol Immunol
    4. (2005). Banham AH: Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell level.
    5. (2009). Cells Promote Cytotoxic T Cell Activation in Tumor Immunity. Immunity
    6. (2006). Cho JH: A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science
    7. (2007). Cutting edge: Th17 and regulatory T cell dynamics and the regulation by IL-2 in the tumor microenvironment.
    8. (2008). DR: The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat. Nat Immunol
    9. (2009). FO: The IL-23/Th17 axis in the immunopathogenesis of psoriasis.
    10. (2006). FS: Circulating and liver resident CD4+CD25 + regulatory T cells actively influence the antiviral immune response and disease progression in patients with hepatitis B.
    11. (2007). FS: Increased infiltration of intrahepatic DC subsets closely correlate with viral control and liver injury in immune active pediatric patients with chronic hepatitis B. Clin Immunol
    12. (2010). FS: Interleukin-17-producing CD4(+) T cells increase with severity of liver damage in patients with chronic hepatitis B. Hepatology
    13. (2005). HL: Regulatory T cells contribute to the impaired immune response in patients with chronic hepatitis B virus infection. Hepatology
    14. (2009). Human memory FOXP3+ Tregs secrete IL-17 ex vivo and constitutively express the T(H)17 lineage-specific transcription factor RORgamma t. Proc Natl Acad Sci USA
    15. (2009). IL-17 and Th17 cells in human inflammatory diseases. Microbes Infect
    16. (2002). Imbalanced intrahepatic expression of interleukin 12, interferon gamma, and interleukin 10 in fulminant hepatitis B. Hepatology
    17. (2008). Immune homeostasis: regulatory T cells (Treg) and molecules.
    18. (2010). Immune-mediated liver injury.
    19. (2005). Immunology of hepatitis B virus and hepatitis C virus infection. Nat Rev Immunol
    20. increases the expression of Toll-like receptor-2, 4, and 9 by increasing IL-1beta and IL-6 production in autoimmune arthritis.
    21. (2009). Lanzavecchia A: Human Th17 cells in infection and autoimmunity. Microbes Infect
    22. (2009). Liu YJ: Identification of IL-17-producing FOXP3+ regulatory T cells in humans. Proc Natl Acad Sci USA
    23. (2008). LR: Interleukin-17-producing T cells are enriched in the joints of children with arthritis, but have a reciprocal relationship to regulatory T cell numbers. Arthritis Rheum
    24. (2007). Piccirillo CA: TGF-beta1 modulates Foxp3 expression and regulatory activity in distinct CD4+ T cell subsets.
    25. (2009). RD: Interplay between the TH17 and TReg cell lineages: a (co-)evolutionary perspective. Nat Rev Immunol
    26. (2007). Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid. Science
    27. (2007). S: T cell self-reactivity forms a cytokine milieu for spontaneous development of IL-17+ Th cells that cause autoimmune arthritis. J Exp Med
    28. (2010). SM: Translational mini-review series on Th17 cells: CD4 T helper cells: functional plasticity and differential sensitivity to regulatory T cell-mediated regulation. Clin Exp Immunol
    29. (2007). T-cell regulation by CD4 regulatory T cells during hepatitis B and C virus infections: facts and controversies. Lancet Infect Dis
    30. (2009). Th17 cells in rheumatoid arthritis and systemic lupus erythematosus.
    31. (2009). The interleukin-17 pathway is involved in human alcoholic liver disease. Hepatology
    32. (2010). The Th17/Treg imbalance exists in patients with heart failure with normal ejection fraction and heart failure with reduced ejection fraction. Clin Chim Acta
    33. (2010). The Treg/Th17 imbalance in patients with idiopathic dilated cardiomyopathy.
    34. (2010). Zheng L: Activated monocytes in peritumoral stroma of hepatocellular carcinoma promote expansion of memory T helper 17 cells. Hepatology

    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.