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Radionuclide imaging with human polyclonal immunoglobulin (99mTc-HIG) and bone scan in patients with rheumatoid arthritis and serum-negative polyarthritis

By G Gerasimou, E Moralidis, E Papanastasiou, G Liaros, T Aggelopoulou, E Triantafyllidou, N Lytras, L Settas and A Gotzamani-Psarrakou


Background and aim: Rheumatoid arthritis (RA) is a chronic polyarthritic syndrome in which actively inflamed joints coexist with others being in remission. Compatible bone scan (BS) reveals joints with increased activity due to degenerative alterations, whilst scanning with human polyclonal immunoglobulin (HIG) is capable to show which of the joints present active inflammation of the synovial membrane. The aim of the study is to investigate the utility of molecular imaging with HIG in patients suffering from RA

Topics: Original Article
Publisher: LITHOGRAPHIA Antoniadis I.-Psarras Th. G.P.
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Provided by: PubMed Central
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