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Memory/effector (CD45RBlo) CD4 T cells are controlled directly by IL-10 and cause IL-22–dependent intestinal pathology

By Masahito Kamanaka, Samuel Huber, Lauren A. Zenewicz, Nicola Gagliani, Chozhavendan Rathinam, William O'Connor, Yisong Y. Wan, Susumu Nakae, Yoichiro Iwakura, Liming Hao and Richard A. Flavell

Abstract

Interleukin-10 acts directly on CD45RBlo but not CD45RBhi cells to control colitis upon transfer into Rag1-deficient recipients

Topics: Article
Publisher: The Rockefeller University Press
OAI identifier: oai:pubmedcentral.nih.gov:3092344
Provided by: PubMed Central

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