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Nuclear β-catenin and CD44 upregulation characterize invasive cell populations in non-aggressive MCF-7 breast cancer cells

By Masahiro Uchino, Hiroko Kojima, Kenta Wada, Mika Imada, Fumitoshi Onoda, Hiroyuki Satofuka, Takahiko Utsugi and Yasufumi Murakami
Topics: Research Article
Publisher: BioMed Central
OAI identifier: oai:pubmedcentral.nih.gov:3087322
Provided by: PubMed Central

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  1. (2006). Altevogt P: CD24 affects CXCR4 function in pre-B lymphocytes and breast carcinoma cells.
  2. (2008). Assoian RK: ABCG2 expression and side population abundance regulated by a transforming growth factor b-directed epithelial-mesenchymal transition. Cancer Res
  3. (2006). Badve S, Nakshatri H: CD44 +/CD24 - breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis. Breast Cancer Res
  4. (2007). Beyond tumorigenesis: cancer stem cells in metastasis. Cell Research
  5. (2007). Blobe GC: The type III TGF-beta receptor suppresses breast cancer progression.
  6. (2003). Botstein D: Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci USA
  7. (2007). Brivanlou AH: Signaling pathways in cancer and embryonic stem cells. Stem Cell Rev
  8. (2007). Chemotropic axon guidance molecules in tumorigenesis. Prog Exp Tumor Res
  9. (2007). Clarke MF: The prognostic role of a gene signature from tumorigenic breast-cancer cells.
  10. (1997). CW: Selection of invasive and metastatic subpopulations from a human lung adenocarcinoma cell line.
  11. (1998). DD: A multidrug resistance transporter from human MCF-7 breast cancer cells. Proc Natl Acad Sci USA
  12. (2008). Dedhar S: Epithelial-mesenchymal transition (EMT) is not sufficient for spontaneous murine breast cancer metastasis. Dev Dyn
  13. (2005). Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors.
  14. (2006). DJ: Cortactin underpins CD44-promoted invasion and adhesion of breast cancer cells to bone marrow endothelial cells. Oncogene
  15. (2005). DJ: Requirement for JAK/STAT signaling throughout border cell migration in Drosophila. Development
  16. (2009). E-cadherin, beta-catenin, and ZEB1 in malignant progression of cancer. Cancer Metastasis Rev
  17. (1998). EG: CD44 expression and growth factors. Front Biosci
  18. (2003). EW: Epidermal growth factor-induced epithelio-mesenchymal transition in human breast carcinoma cells. Lab Invest
  19. (2006). EW: The epithelial-mesenchymal transition: new insights in signaling, development, and disease.
  20. (2006). Functional crossmodulation between SOCS proteins can stimulate cytokine signaling.
  21. (2001). Furcht LT: Progression and enhancement of metastatic potential after exposure of tumor cells to chemotherapeutic agents. Cancer Res
  22. (2006). Gene expression profiling of breast cell lines identifies potential new basal markers. Oncogene
  23. (1996). Horwitz A: Cell migration: a physiologically integrated molecular process. Cell
  24. (2000). HR: Polarization of chemoattractant receptor signaling during neutrophil chemotaxis. Science
  25. (2008). Human breast cancer cell lines contain stemlike cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy. Breast Cancer Res
  26. (2010). KH: Wnt/beta-catenin pathway activation is enriched in basal- like breast cancers and predicts poor outcome.
  27. (1977). Kripke ML: Metastasis results from preexisting variant cells within a malignant tumour. Science
  28. (2008). Kuwano H: Nuclear beta-catenin expression at the invasive front and in the vessels predicts liver metastasis in colorectal carcinoma. Anticancer Res
  29. (2007). LH: Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel. Cancer Res
  30. (2003). LM: The two faces of transforming growth factor b in carcinogenesis.
  31. (2007). Löwik CW, van der Pluijm G: Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer. Cancer Res
  32. (2003). Matsukura S: A role for CD44 in an antigen-induced murine model of pulmonary eosinophilia.
  33. (2006). Mesenchymal-to-epithelial transition facilitates bladder cancer metastasis: role of fibroblast growth factor receptor-2. Cancer Res
  34. (2003). MF: Prospective identification of tumorigenic breast cancer cells.
  35. (2005). MG: Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties. Cancer Res
  36. (2005). Migrating cancer stem cells - an integrated concept of malignant tumor progression. Nat Rev Cancer
  37. (2003). Neuregulin-1 enhances motility and migration of human astrocytic glioma cells.
  38. (2005). Newgreen DF: The fallacy of epithelial mesenchymal transition in neoplasia. Cancer Res
  39. (1999). NP: New insights into the biology of the acute phase response.
  40. (2002). P: MEK1 signaling mediates transformation and metastasis of EpH4 mammary epithelial cells independent of an epithelial to mesenchymal transition. Cancer Res
  41. (2008). Pals ST: Deletion of the WNT target and cancer stem cell marker CD44 in Apc(Min/+) mice attenuates intestinal tumorigenesis. Cancer Res
  42. (1999). Pals ST: Expression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathway.
  43. (2001). Phillips WA: The phosphatidylinositol 3’-kinase p85a genes is an oncogene in human ovarian and colon tumors. Cancer Res
  44. (2007). PK: Estrogen promotes reversible epithelial-tomesenchymal-like transition and collective motility in MCF-7 breast cancer cells.
  45. (2008). RA: The epithelial-messenchymal transition generates cells with properties of stem cells. Cell
  46. (2006). Rajasekaran AK: Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis. Cancer Res
  47. (1992). RB: Association of increased basement membrane invasiveness with absence of estrogen receptor and expression of vimentin in human breast cancer cell lines.
  48. (2000). SA: Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis.
  49. (2009). Savagner P: Epithelial-mesenchymal transition: a cancer researcher’s conceptual friend and foe.
  50. (2003). Significance of E-cadherin/beta-catenin complex and cyclin D1 in breast cancer. Oncol Rep 2002, 9:915-928. Uchino et al.
  51. (2007). TA: BMP7: a new bone metastases prevention?
  52. (1990). Transforming growth factor b stimulates mammary adenocarcinoma cell invasion and metastatic potential.
  53. (2007). Zhang Y: Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance. Proc Natl Acad Sci USA
  54. (2001). Zlotnik A: Involvement of chemokine receptors in breast cancer metastasis. Nature
  55. (2006). ZR: P68 RNA helicase mediates PDGF-induced epithelial mesenchymal transition by displacing Axin from beta-catenin. Cell