Article thumbnail

PAR proteins diffuse freely across the anterior–posterior boundary in polarized C. elegans embryos

By Nathan W. Goehring, Carsten Hoege, Stephan W. Grill and Anthony A. Hyman


FRAP reveals that a stable PAR boundary requires balancing diffusive flux of PAR proteins between domains with spatial differences in PAR protein membrane affinities

Topics: Research Articles
Publisher: The Rockefeller University Press
OAI identifier:
Provided by: PubMed Central

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.

Suggested articles


  1. (2005). Asymmetric enrichment of PIE-1 in the Caenorhabditis elegans zygote mediated by binary counterdiffusion.
  2. (2010). elegans polarity determinant Par-6 links Rac and Cdc42 to PKCzeta signaling and cell transformation.
  3. (2009). Fgf8 morphogen gradient forms by a source-sink
  4. (2009). Germline P granules are liquid droplets that localize by controlled dissolution/condensation.
  5. (2006). Interaction of PAR-6 with CDC42 is required for maintenance but not establishment of PAR asymmetry
  6. (2003). Myosin and the PAR proteins polarize microfilament-dependent forces that shape and position mitotic spindles in Caenorhabditis elegans.
  7. (2000). Plasma membrane compartmentalization in yeast by messenger RNA transport and a septin diffusion barrier.
  8. (2009). Polarization of the C. elegans zygote proceeds via distinct establishment and maintenance phases.
  9. (2003). Spontaneous cell polarization through actomyosin-based delivery of the Cdc42 GTPase.
  10. (1999). The nonmuscle myosin regulatory light chain gene mlc-4 is required for cytokinesis, anterior-posterior polarity, and body morphology during Caenorhabditis elegans embryogenesis.