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PAR proteins diffuse freely across the anterior–posterior boundary in polarized C. elegans embryos

By Nathan W. Goehring, Carsten Hoege, Stephan W. Grill and Anthony A. Hyman

Abstract

FRAP reveals that a stable PAR boundary requires balancing diffusive flux of PAR proteins between domains with spatial differences in PAR protein membrane affinities

Topics: Research Articles
Publisher: The Rockefeller University Press
OAI identifier: oai:pubmedcentral.nih.gov:3087016
Provided by: PubMed Central

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Citations

  1. (2005). Asymmetric enrichment of PIE-1 in the Caenorhabditis elegans zygote mediated by binary counterdiffusion.
  2. (2010). elegans polarity determinant Par-6 links Rac and Cdc42 to PKCzeta signaling and cell transformation.
  3. (2009). Fgf8 morphogen gradient forms by a source-sink
  4. (2009). Germline P granules are liquid droplets that localize by controlled dissolution/condensation.
  5. (2006). Interaction of PAR-6 with CDC42 is required for maintenance but not establishment of PAR asymmetry
  6. (2003). Myosin and the PAR proteins polarize microfilament-dependent forces that shape and position mitotic spindles in Caenorhabditis elegans.
  7. (2000). Plasma membrane compartmentalization in yeast by messenger RNA transport and a septin diffusion barrier.
  8. (2009). Polarization of the C. elegans zygote proceeds via distinct establishment and maintenance phases.
  9. (2003). Spontaneous cell polarization through actomyosin-based delivery of the Cdc42 GTPase.
  10. (1999). The nonmuscle myosin regulatory light chain gene mlc-4 is required for cytokinesis, anterior-posterior polarity, and body morphology during Caenorhabditis elegans embryogenesis.