Article thumbnail

A Central Role for CD68(+) Macrophages in Hepatopulmonary Syndrome: Reversal by Macrophage Depletion

By Thenappan Thenappan, Ankush Goel, Glenn Marsboom, Yong-Hu Fang, Peter T. Toth, Hannah J. Zhang, Hidemi Kajimoto, Zhigang Hong, Jonathan Paul, Christian Wietholt, Jennifer Pogoriler, Lin Piao, Jalees Rehman and Stephen L. Archer


Rationale: The etiology of hepatopulmonary syndrome (HPS), a common complication of cirrhosis, is unknown. Inflammation and macrophage accumulation occur in HPS; however, their importance is unclear. Common bile duct ligation (CBDL) creates an accepted model of HPS, allowing us to investigate the cause of HPS

Topics: F. Pulmonary Vascular Disease
Publisher: American Thoracic Society
OAI identifier:
Provided by: PubMed Central
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://www.pubmedcentral.nih.g... (external link)

  • To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.

    Suggested articles