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Epithelial Cell Death Is an Important Contributor to Oxidant-mediated Acute Lung Injury

By G. R. Scott Budinger, Gökhan M. Mutlu, Daniela Urich, Saul Soberanes, Leonard J. Buccellato, Keenan Hawkins, Sergio E. Chiarella, Kathryn A. Radigan, James Eisenbart, Hemant Agrawal, Sara Berkelhamer, Siegfried Hekimi, Jianke Zhang, Harris Perlman, Paul T. Schumacker, Manu Jain and Navdeep S. Chandel

Abstract

Rationale: Acute lung injury and the acute respiratory distress syndrome are characterized by increased lung oxidant stress and apoptotic cell death. The contribution of epithelial cell apoptosis to the development of lung injury is unknown

Topics: C. Critical Care
Publisher: American Thoracic Society
OAI identifier: oai:pubmedcentral.nih.gov:3086743
Provided by: PubMed Central
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