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Radiation damage in single-particle cryo-electron microscopy: effects of dose and dose rate

By Manikandan Karuppasamy, Fatemeh Karimi Nejadasl, Milos Vulovic, Abraham J. Koster and Raimond B. G. Ravelli

Abstract

The effects of dose and dose-rate were investigated for single-particle cryo-electron microscopy using stroboscopic data collection. A dose-rate effect was observed favoring lower flux densities

Topics: Radiation Damage
Publisher: International Union of Crystallography
OAI identifier: oai:pubmedcentral.nih.gov:3083915
Provided by: PubMed Central
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    1. (2010). Acta Cryst.
    2. (2000). Acta Cryst. D56, 1413–1420. radiation damage
    3. (2007). Electron Crystallography of Biological Macromolecules.
    4. (2008). radiation damage 412 Manikandan Karuppasamy et al. Radiation damage in cryo-electron microscopy

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