Article thumbnail

Giant Hemosiderotic Dermatofibroma: A Case Report and Review of the Literature

By Marc Pusztaszeri, Pierre-Yves Jaquet and Carole Williamson


Dermatofibroma is a common benign fibrohistiocytic lesion that usually appears as a slow-growing, firm dermal nodule with a predilection for the legs of middle-aged women. They are usually smaller than 2 cm in diameter. Many histological variants have been described. Generally, the clinical and histological diagnosis is straightforward, but differentiating it from other cutaneous tumors can be difficult in atypical cases and rare variants. Giant dermatofibroma is a rare clinical variant of dermatofibroma and less than 25 cases have been reported. It is characterized essentially by its unusually large size, which often mimics malignant tumors clinically. We first present the case of a giant hemosiderotic dermatofibroma in a 54-year-old patient, who presented with a large ulcerated mass of the left foot which was excised, and then review the literature briefly

Topics: Published: February 2011
Publisher: S. Karger AG
OAI identifier:
Provided by: PubMed Central

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.

Suggested articles


  1. A: Rapidly evolving giant dermatofibroma.
  2. (1991). de Moragas JM: Atypical polypoid dermatofibroma: report of two cases.
  3. (2006). F: A case of ‘giant’ aneurysmal benign fibrous histiocytoma. Clin Exp Dermatol
  4. (2007). Giant dermatofibroma: a rare variant of dermatofibroma preferentially developing on the lower limbs. Clin Exp Dermatol
  5. (1995). Giant xanthomatous dermatofibroma – a case distinguished histologically and immunohistochemically from invasive fibrohistiocytic tumors. Dermatology
  6. (2007). Guillén C: Giant dermatofibroma: case report and review of the literature. Actas Dermosifiliogr
  7. Hemosiderotic dermatofibroma: report of one case.
  8. (2000). HL: Dermatofibroma is a clonal proliferative disease.
  9. JK: Giant dermatofibroma with granular cell changes: side-effect of bee-venom acupuncture?
  10. Perkins AS: Clonal analysis of cutaneous fibrous histiocytoma (dermatofibroma).
  11. S: Dermoscopic findings of haemosiderotic and aneurysmal dermatofibroma: report of six patients.
  12. (1994). Sánchez Yus E: Giant dermatofibroma: a little-known clinical variant of dermatofibroma.