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Loss of TRPC1-mediated Ca2+ influx contributes to impaired degranulation in Fyn-deficient mouse bone marrow-derived mast cells

By Ryo Suzuki, Xibao Liu, Ana Olivera, Lizath Aguiniga, Yumi Yamashita, Ulrich Blank, Indu Ambudkar and Juan Rivera

Abstract

Fyn-dependent expression of the cationic transient receptor potential channel 1 contributes to mast cell Ca2+ influx, cortical F-actin depolymerization, and degranulation

Topics: Spotlight on Leading Edge Research
Publisher: Society for Leukocyte Biology
OAI identifier: oai:pubmedcentral.nih.gov:3072234
Provided by: PubMed Central
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