Article thumbnail

Selective nociceptor activation in volunteers by infrared diode laser

By Alexander Z Tzabazis, Michael Klukinov, Sonia Crottaz-Herbette, Mikhail I Nemenov, Martin S Angst and David C Yeomans
Topics: Research
Publisher: BioMed Central
OAI identifier:
Provided by: PubMed Central

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.

Suggested articles


  1. (2001). A new method for measuring the conduction velocities of Abeta-, Adelta- and C-fibers following electric and CO(2) laser stimulation in humans. Neurosci Lett
  2. (1983). A: A model for the temperature distribution in skin noxiously stimulated by a brief pulse of CO2 laser radiation.
  3. (1988). Bjerring P: Laser-induced pain for evaluation of local analgesia: a comparison of topical application (EMLA) and local injection (lidocaine). Anesth Analg
  4. (1988). Bjerring P: Sensory and pain threshold characteristics to laser stimuli.
  5. (2003). Cruccu G: Evidence of a specific spinal pathway for the sense of warmth in humans.
  6. (2005). DC: Differential activation of trigeminal C or Adelta nociceptors by infrared diode laser in rats: behavioral evidence. Brain Res
  7. (1967). ER: Myelinated afferent fibres responding specifically to noxious stimulation of the skin.
  8. (2009). Greenspan JD: Differential brain activation associated with laser-evoked burning and pricking pain: An event-related fMRI study. Pain
  9. (2005). KL: Thermoreceptive innervation of human glabrous and hairy skin: a contact heat evoked potential analysis. Pain
  10. (2010). Le Bars D: The fine tuning of pain thresholds: a sophisticated double alarm system. PLoS One
  11. (1991). M: CO2 laser-induced pain-related somatosensory evoked potentials in peripheral neuropathies: correlation between electrophysiological and histopathological findings. Muscle Nerve
  12. (2005). Mouraux A: EEG and laser stimulation as tools for pain research. Curr Opin Investig Drugs
  13. (2003). Mouraux A: How do we selectively activate skin nociceptors with a high power infrared laser? Physiology and biophysics of laser stimulation. Neurophysiol Clin
  14. (1982). Nociceptors and warm receptors innervated by C fibres in human skin.
  15. (1939). pain and tickling: an electro-physiological investigation on cutaneous sensory nerves.
  16. (2000). Pain-Related somatosensory evoked potentials.
  17. (1996). Proudfit HK: Nociceptive responses to high and low rates of noxious cutaneous heating are mediated by different nociceptors in the rat: behavioral evidence. Pain
  18. (1996). Proudfit HK: Nociceptive responses to high and low rates of noxious cutaneous heating are mediated by different nociceptors in the rat: electrophysiological evidence. Pain
  19. (1995). Response of C fibre nociceptors in the anaesthetized monkey to heat stimuli: estimates of receptor depth and threshold.
  20. (1983). Response properties of thin myelinated (A-delta) fibers in human skin nerves.
  21. (1973). RG: Perceptual changes accompanying controlled preferential blocking of A and C fibre responses in intact human skin nerves. Exp Brain Res
  22. (1980). RH: A psychophysical analysis of experimential factors that selectively influence the affective dimension of pain. Pain
  23. (1991). RH: Neurogenic hyperalgesia: the search for the primary cutaneous afferent fibers that contribute to capsaicin-induced pain and hyperalgesia.
  24. (2011). Treede RD: Clinical evaluation criteria for the assessment of impaired pain sensitivity by thulium-laser evoked potentials. Clin Neurophysiol 2000, 111:725-735. Tzabazis et al. Molecular Pain
  25. (2002). Treede RD: Inward currents in primary nociceptive neurons of the rat and pain sensations in humans elicited by infrared diode laser pulses. Pain
  26. (1984). Treede RD: Nerve fibre discharges, cerebral potentials and sensations induced by CO2 laser stimulation. Hum Neurobiol
  27. (1984). Treede RD: Responses of human cutaneous afferents to CO2 laser stimuli causing pain. Exp Brain Res
  28. (1976). VB: A laser stimulator for the study of cutaneous thermal and pain sensations.
  29. (1996). Vierck CJ: Effects of systemic morphine on responses of primates to first or second pain sensations. Pain
  30. (2010). Yeomans DC: Thermal nociceptive properties of trigeminal afferent neurons in rats.