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Ultrastructural, Immunofluorescence, and RNA Evidence Support the Hypothesis of a “New” Virus Associated With Kawasaki Disease

By Anne H. Rowley, Susan C. Baker, Stanford T. Shulman, Kenneth H. Rand, Maria S. Tretiakova, Elizabeth J. Perlman, Francesca L. Garcia, Nuzhath F. Tajuddin, Linda M. Fox, Julia H. Huang, J Carter Ralphe, Kei Takahashi, Jared Flatow, Simon Lin, Mitra B. Kalelkar, Benjamin Soriano and Jan M. Orenstein

Abstract

Background. Intracytoplasmic inclusion bodies (ICI) have been identified in ciliated bronchial epithelium of Kawasaki disease (KD) patients using a synthetic antibody derived from acute KD arterial IgA plasma cells; ICI may derive from the KD etiologic agent

Topics: Major Articles and Brief Reports
Publisher: Oxford University Press
OAI identifier: oai:pubmedcentral.nih.gov:3068030
Provided by: PubMed Central
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