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Mycobacterium tuberculosis Can Utilize Heme as an Iron Source▿

By Christopher M. Jones and Michael Niederweis

Abstract

Most iron in mammals is found within the heme prosthetic group. Consequently, many bacterial pathogens possess heme acquisition systems to utilize iron from the host. Here, we demonstrate that Mycobacterium tuberculosis can utilize heme as an iron source, suggesting that M. tuberculosis possesses a yet-unknown heme acquisition system

Topics: Physiology and Metabolism
Publisher: American Society for Microbiology (ASM)
OAI identifier: oai:pubmedcentral.nih.gov:3067660
Provided by: PubMed Central
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