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The Probiotic Escherichia coli Nissle 1917 Reduces Pathogen Invasion and Modulates Cytokine Expression in Caco-2 Cells Infected with Crohn's Disease-Associated E. coli LF82 ▿

By Claudia Huebner, Yaoyao Ding, Ivonne Petermann, Christoph Knapp and Lynnette R. Ferguson


Increased numbers of adherent invasive Escherichia coli (AIEC) have been found in Crohn's disease (CD) patients. In this report, we investigate the potential of the probiotic Escherichia coli Nissle 1917 (EcN) to reduce features associated with AIEC pathogenicity in an already established infection with AIEC reference strain LF82

Topics: Food Microbiology
Publisher: American Society for Microbiology (ASM)
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Provided by: PubMed Central
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