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Mutations in Complement Regulatory Proteins Predispose to Preeclampsia: A Genetic Analysis of the PROMISSE Cohort

By Jane E. Salmon, Cara Heuser, Michael Triebwasser, M. Kathryn Liszewski, David Kavanagh, Lubka Roumenina, D. Ware Branch, Tim Goodship, Veronique Fremeaux-Bacchi and John P. Atkinson


Jane Salmon and colleagues studied 250 pregnant patients with SLE and/or antiphospholipid antibodies and found an association of risk variants in complement regulatory proteins in patients who developed preeclampsia, as well as in preeclampsia patients lacking autoimmune disease

Topics: Research Article
Publisher: Public Library of Science
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Provided by: PubMed Central

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