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Leiomyoma in the posterior choroid: a case report.

By Yoon Kyung Jeon, Hee Joung Cha, Na Rae Kim, Chong Jai Kim and Je G. Chi


Smooth muscle tumor of the uveal tract is rare, and mostly located in the cilio-choroidal area. We report a unique case of posterior choroidal leiomyoma in a 27-yr-old man. Ophthalmoscopic examination disclosed an 11 mm-sized mass on the fundus two-disc diameters apart from the optic disc. With a suspicion of amelanotic melanoma, the globe was enucleated. The mass occupied the whole thickness of choroidal stroma beneath the pigmented retinal epithelium and composed of spindle cells arranged in intersecting fascicles. Immunohistochemical studies demonstrated immunoreactivities of the tumor cells for smooth muscle actin, desmin, and vimentin. Ultrastructurally, numerous intracytoplasmic filaments with fusiform focal densities, scattered segmental external laminae, subplasmalemmal densities, and pinocytic vesicles were noted. The leiomyoma in this case had several unusual features in that it was confined to the posterior choroid with no relation to the ciliary body, occupied the whole stroma of the choroid instead of suprauveal location, and occurred in a young male. It is important to include choroidal leiomyoma in the differential diagnosis of choroidal tumors

Topics: Research Article
Publisher: Korean Academy of Medical Sciences
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Provided by: PubMed Central

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  1. (1994). Are most intraocular “leiomyomas" really melanocytic lesions? Ophthalmology
  2. (1976). Choroidal leiomyoma of vascular origin.
  3. (1999). Choroidal leiomyoma: report of a case. Retina
  4. (1989). Clinical and pathological status of mesectodermal leiomyoma of the ciliary body: a case report and review of the literature. Graefes Arch Clin Exp Ophthalmol
  5. (1998). Endoresection of a ciliary body leiomyoma.
  6. (1997). Leiomyoma of the choroid. Presented at the seventh biennial meeting of the Association of Ophthalmic Alumni, Armed Forces Institute of Pathology;
  7. (2000). Leiomyoma of the ciliary body extending to the anterior chamber: clinicopathologic and ultrasound biomicroscopic correlation. Surv Ophthalmol
  8. (1968). Leiomyoma of the ciliary body. Electron microscopic verification.
  9. (1977). Mesectodermal leiomyoma of the ciliary body: a tumor of presumed neural crest origin. Cancer
  10. (1985). Mesectodermal leiomyoma of the ciliary body: an ultrastructural study. Arch Ophthalmol
  11. (1989). Mesectodermal leiomyoma of the ciliary body: case report.
  12. (1990). Mesectodermal leiomyoma of the ciliary body: new evidence for neural crest origin.
  13. (1994). Observations on seven cases of intraocular leiomyoma: the 1993 Byron Demorest Lecture. Arch Ophthalmol
  14. (1984). The persisting pseudomelanoma problem. Arch Ophthalmol
  15. (1990). The uveal tract. In:
  16. (1991). Transscleral leiomyoma. Ophthalmology