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Methyl 2-(1H-indole-3-carboxamido)­acetate

By Fang Hu, Le Zheng, Xiang Chao Zeng and Kai Ping Li


The title compound, C12H12N2O3, was synthesized by condensation of methyl amino­acetate with 3-trichloro­acetyl­indole. In the crystal, inter­molecular N—H⋯O hydrogen bonds link the mol­ecules into chains parallel to the b axis. The chains are further connected into a three-dimensional network by N—H⋯O hydrogen bonds involving the indole N atom. In the molecule, the indole skeleton is nearly planar [maximum deviation = 0.012 (1) Å] and the mean plane of the amido group is twisted from the mean plane of indole ring by 17.2 (1)°

Topics: Organic Papers
Publisher: International Union of Crystallography
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Provided by: PubMed Central

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