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1-[2-(4-Nitro­phen­yl)-5-(5-phenyl-1,2-oxazol-3-yl)-1,2,3,4-tetra­hydro­quinolin-4-yl]pyrrolidin-2-one monohydrate

By Margarita Gutierrez, Gabriel Vallejos, Carlos Fernández, Alejandro Cárdenas and Iván Brito


The title compound, C28H24N4O4·H2O, crystallizes with two organic mol­ecules and two solvent water mol­ecules in the asymmetric unit. The most obvious difference between the mol­ecules is the torsion angles between the isoxazole ring and the benzene and phenyl rings [47.0 (2)/56.4 (2) and 33.3 (2)/11.0 (2)°, respectively]. Another important difference is observed in the rotation of the nitro group with respect to the phenyl groups [3.5 (6) and 31.1 (6)°]. The pyrrolidinone fragment is cis oriented with respect to the 4-nitro­phenyl fragment. In the crystal, mol­ecules are linked into centrosymmetric R 4 2(8) and R 4 4(20) motifs by O—H⋯O and N—H⋯O inter­actions

Topics: Organic Papers
Publisher: International Union of Crystallography
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Provided by: PubMed Central

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