Article thumbnail

Multi-omics approach to study the growth efficiency and amino acid metabolism in Lactococcus lactis at various specific growth rates

By Petri-Jaan Lahtvee, Kaarel Adamberg, Liisa Arike, Ranno Nahku, Kadri Aller and Raivo Vilu
Topics: Research
Publisher: BioMed Central
OAI identifier:
Provided by: PubMed Central

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.

Suggested articles


  1. (2001). A: The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403. Genome Research
  2. (2001). AJ: AAA+ superfamily ATPases: common structure -diverse function. Gen Cells
  3. (1989). AJ: Bioenergetics and solute transport in lactococci. Crit Rev Microbiol
  4. (1996). Amino acid utilization by Lactococcus lactis subsp. cremoris FD1 during growth on yeast extract or casein peptone.
  5. (2006). BC: Identification of the leucine-to-2-methylbutyric acid catabolic pathway of Lactococcus lactis. Appl Environ Microbiol
  6. (2008). Carbon catabolite repression in bacteria: many ways to make the most out of nutrients. Nat Rev Microbiol
  7. (1997). Control of the shift from homolactic acid to mixed-acid fermentation in Lactococcus lactis: predominant role of the NADH/NAD + ratio.
  8. (2006). Differential expression of proteins and genes in the lag phase of Lactococcus lactis subsp. lactis grown in synthetic medium and reconstituted skim milk. Appl Envir Microbiol
  9. (2002). Global control of sugar metabolism: a grampositive solution. Antonie Van Leeuwenhoek
  10. (2008). Growth rate regulated genes and their wide involvement in the Lactococcus lactis stress responses.
  11. (2007). Ishihama Y: Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips. Nat Prot
  12. (1988). Konings WN: Relation of growth of Streptococcus lactis and Streptococcus cremoris to amino acid transport.
  13. (1990). Konings WN: Relationship between utilization of proline and proline-containing peptides and growth of Lactococcus lactis.
  14. (2009). Lactococcus lactis as a live vector for mucosal delivery of therapeutic proteins. Human Vaccines
  15. (1998). Loubiere P: Glutamate biosynthesis in Lactococcus lactis subsp. lactis NCDO 2118. Appl Envir Microbiol
  16. (2010). Loubière P: Glutamate-induced metabolic changes in Lactococcus lactis NCDO 2118 during GABA production: combined transcriptomic and proteomic analysis. Amino Acids
  17. (2000). Loubiere P: The metabolic network of Lactococcus lactis: Distribution of 14C-labeled substrates between catabolic and anabolic pathways.
  18. (2009). MassMatrix: a database search program for rapid characterization of proteins and peptides from tandem mass spectrometry data. Proteom
  19. (2009). Mechtler K: High precision quantitative proteomics using iTRAQ on an LTQ Orbitrap: a new mass spectrometric method combining the benefits of all.
  20. (2002). Metabolic engineering of lactic acid bacteria for the production of nutraceuticals. Antonie Van Leeuwenhoek
  21. (2002). Metabolic engineering of Lactococcus lactis: the impact of genomics and metabolic modelling.
  22. (1997). Metabolism and energetics of Lactococcus lactis during growth in complex or synthetic media. Appl Environ Microbiol
  23. (1993). Minimal Requirements for Exponential Growth of Lactococcus lactis.
  24. (2005). Modeling Lactococcus lactis using a genome-scale flux model.
  25. (2008). Poquet I: Lactococcus lactis, an efficient cell factory for recombinant protein production and secretion.
  26. (2005). PRIDE: the proteomics identifications database. Proteomics
  27. (2009). Quasi steady state growth of Lactococcus lactis in glucose-limited acceleration stat (A-stat) cultures. Antonie van Leeuwenhoek
  28. (1951). RJ: Protein measurement with the Folin phenol reagent.
  29. (1991). Statistical treatment for rejection of deviant values: critical values of Dixon’s “Q” parameter and related subrange ratios at the 95% confidence level. Analyt Chem
  30. (2010). Systems biology approach reveals that overflow metabolism of acetate in Escherichia coli is triggered by carbon catabolite repression of acetylCoA synthetase.
  31. (2009). Teusink B: Shifts in growth strategies reflect tradeoffs in cellular economics. Mol Syst Biol
  32. (2009). The D-2-hydroxyacid dehydrogenase incorrectly annotated PanE is the sole reduction system for branched-chain 2-keto acids in Lactococcus lactis.
  33. (2007). The energy spilling reactions of bacteria and other organisms.
  34. (2008). The lactic acid bacterium as a cell factory for food ingredient production.
  35. (2009). Transcriptome and proteome exploration to model translation efficiency and protein stability in Lactococcus lactis. PLoS Comput Biol
  36. (2009). Using highly efficient nonlinear experimental design methods for optimization of Lactococcus lactis fermentation in chemically defined media. Biotechnol Prog
  37. (2009). Vilu R: Steady state growth space study of Lactococcus lactis in D-stat cultures. Antonie Van Leeuwenhoek
  38. (2010). Vilu R: UPLC/MS based method for quantitative determination of fatty acid composition in Gram-negative and Gram-positive bacteria.