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Analog insulin detemir for patients with type 1 and type 2 diabetes: a review

By Gregory E Peterson
Topics: Review
Publisher: Dove Medical Press
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Provided by: PubMed Central

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  11. (2008). Insulin detemir in type 1 and type 2 diabetes [abstract]. Ehrlich II World Congress,
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  17. Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes. The Diabetes Control and Complications Trial/
  18. Intensive Glycemic Control in the ACCORD and ADVANCE Trials.
  19. (2004). Intensive integrated therapy of type 2 diabetes: implications for long-term prognosis. Diabetes.
  20. (2006). Intermediate and long-acting insulins: a review of NPH insulin, insulin glargine and insulin detemir. Curr Med Res Opin.
  21. (2008). Less weight gain and hypoglycaemia with once-daily insulin detemir than NPH insulin in intensification of insulin therapy in overweight Type 2 diabetes patients: the PREDICTIVE BMI clinical trial. Diabet Med.
  22. (2005). Lower within-subject variability of fasting blood glucose and reduced weight gain with insulin detemir compared to NPH insulin in patients with type 2 diabetes. Diabetes Obes Metab.
  23. Meta-analysis of effects of intensive blood-glucose control on late complications of type I diabetes.
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  26. (2002). Sulfonylurea inadequacy: efficacy of addition of insulin over 6 years in patients with type 2 diabetes in the UK. Prospective Diabetes Study (UKPDS 57). Diabetes Care.
  27. Targeting postprandial hyperglycemia.
  28. (1996). The Diabetes Control and Complications Trial Research Group. The absence of a glycemic threshold for the development of long-term complications.
  29. (1993). The effect of long-term intensified insulin treatment of microvascular complications of diabetes mellitus.