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Cell Therapy for Cardiovascular Disease: A Comparison of Methods of Delivery

By Nabil Dib, Harris Khawaja, Samantha Varner, Megan McCarthy and Ann Campbell


The field of myocardial regeneration utilizing novel cell-based therapies, gene transfer, and growth factors may prove to play an important role in the future management of ischemic heart disease and cardiomyopathy. Phases I and II clinical trials have been published for a variety of biologics utilizing four methods of delivery: systemic infusion, intracoronary infusion, transvenous coronary sinus, and intramyocardial. This review discusses the advantages and disadvantages of the delivery approaches above

Topics: Article
Publisher: Springer US
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Provided by: PubMed Central

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