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Effect of nitric oxide on mitochondrial activity of human synovial cells

By Berta Cillero-Pastor, Miguel A Martin, Joaquín Arenas, María J López-Armada and Francisco J Blanco
Topics: Research Article
Publisher: BioMed Central
OAI identifier: oai:pubmedcentral.nih.gov:3045396
Provided by: PubMed Central

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  1. (2006). AA: Prevalence of anti-3-nitrotyrosine antibodies in the joint synovial fluid of patients with rheumatoid arthritis, osteoarthritis and systemic lupus erythematosus. Clin Chim Acta
  2. (2005). Caspase-dependent and -independent cell death pathways after DNA damage. Oncol Rep
  3. (2004). Cell death in cartilage. Osteoarthritis Cartilage
  4. (2007). Constitutive NADPH oxidase and increased mitochondrial respiratory chain activity regulate chemokine gene expression.
  5. (2006). de Lest C: Nitrite and nitrotyrosine concentrations in articular cartilage, subchondral bone, and trabecular bone of normal juvenile, normal adult, and osteoarthritic adult equine metacarpophalangeal joints.
  6. (2007). E: The role of nitric oxide in osteoarthritis.
  7. (1999). Ekindjian OG: Apoptosis induced by nitric oxide is associated with nuclear p53 protein expression in cultured osteoarthritic synoviocytes. Osteoarthritis Cartilage
  8. (1997). Ekindjian OG: Nitric oxide as S-nitrosoproteins in rheumatoid arthritis. Arthritis Rheum
  9. (1998). Firestein GS: Regulation of synoviocyte proliferation, apoptosis, and invasion by the p53 tumor suppressor gene.
  10. (2005). FJ: Effect of nitric oxide on mitochondrial respiratory activity of human articular chondrocytes. Ann Rheum Dis
  11. (2004). FJ: Fisiopatología de la artrosis. Rev Esp Reum
  12. (2003). FJ: Mitochondrial respiratory activity is altered in osteoarthritic human articular chondrocytes. Arthritis Rheum
  13. (2011). FJ: Role of European mitochondrial DNA haplogroups in the prevalence of hip osteoarthritis in Galicia, Northern Spain. Ann Rheum Dis 2010, 69:210-3. Cillero-Pastor et al. BMC Musculoskeletal Disorders
  14. (2005). GE: Somatic mutations in the mitochondria of rheumatoid arthritis synoviocytes. Arthritis Res Ther
  15. (2007). Goldring SR: Osteoarthritis.
  16. (2000). Hernvann A: Nitric oxide modifies glycolytic pathways in cultured human synoviocytes. Cell Biol Int.
  17. (1993). Higgs A: The L-Arginine-Nitric Oxide Pathway.
  18. (2008). HK: Mitochondria-dependent reactive oxygen species-mediated programmed cell death induced by 3,3’-diindolylmethane through inhibition of F0F1-ATP synthase in unicellular protozoan parasite Leishmania donovani. Mol Pharmacol
  19. (2004). Inflammation in osteoarthritis.
  20. (2002). JP: Nitric oxide induced cell death in human osteoarthritic synoviocytes is mediated by tyrosine kinase activation and hydrogen peroxide and/or superoxide formation.
  21. (1996). Liew FY: Production of nitric oxide in the synovial membrane of rheumatoid and osteoarthritis patients.
  22. (2002). Loeser RF: Nitric oxide-mediated chondrocyte cell death requires the generation of additional reactive oxygen species. Arthritis Rheum
  23. (2008). López-Armada MJ: Mitochondrial dysfunction activates cyclooxygenase 2 expression in cultured normal human chondrocytes. Arthritis Rheum
  24. (1995). Miyasaka N: Nitric oxide production and inducible nitric oxide synthase expression in inflammatory arthritides.
  25. (2009). Mobasheri A: The contribution of the synovium, synovial derived inflammatory cytokines and neuropeptides to the pathogenesis of osteoarthritis.
  26. (1995). Nitric oxide and its role in orthopaedic disease. Clin Orthop
  27. (2007). Nitric oxide from both exogenous and endogenous sources activates mitochondriadependent events and induces insults to human chondrocytes.
  28. (2001). Nitric oxide regulates mitochondrial respiration and functions of articular chondrocytes. Arthritis Rheum
  29. (2008). NM: Mitochondria potential, bax “activation,” and programmed cell death. Methods Mol Biol
  30. (2004). Peroxynitrite mediates calcium-dependent mitochondrial dysfunction and cell death via activation of calpains.
  31. (2000). RM: Bcl-2 expression in synovial fibroblasts is essential for maintaining mitochondrial homeostasis and cell viability.
  32. (2009). Role of mitochondria in neurodegenerative diseases: mitochondria as a therapeutic target in Alzheimer’s disease. CNS Spectr
  33. (2008). Slack RS: Mcl-1 is a key regulator of apoptosis during CNS development and after DNA damage.
  34. (2006). SM: Increased oxidative stress in lambs with increased pulmonary blood flow and pulmonary hypertension: role of NADPH oxidase and endothelial NO synthase. Am J Physiol Lung Cell Mol Physiol
  35. (1994). The inducible production of nitric oxide by articular cell types. Osteoarthritis Cartilage
  36. (2009). The mitochondrial death pathway: A promising therapeutic target in Diseases.
  37. The pathology of osteoarthritis. In Osteoarthritis: diagnosis and medical/surgical management. Edited by: Moskowitz RW,
  38. (2004). The pathophysiology of mitochondrial cell death. Science
  39. (2009). TP: Plasma 3-nitrotyrosine is a biomarker in animal models of arthritis: Pharmacological dissection of iNOS’ role in disease. Nitric Oxide
  40. (2007). Welkerling H: Pathobiology of osteoarthritis: pathomechanisms and potential therapeutic targets. Curr Drug Targets