A candidate precursor to serous carcinoma that originates in the distal fallopian tube.
A pathologist’s road map to benign, precancerous, and malignant intraepithelial proliferations in the fallopian tube. Adv Anat Pathol.
Bringing the p53 signature into focus.
(2010). Cancer statistics,
(2006). Clinical behavior of stage II–IV low-grade serous carcinoma of the ovary. Obstet Gynecol.
development of lowgrade ovarian serous carcinoma.
Diverse tumorigenic pathways in ovarian serous carcinoma.
Fallopian tube carcinoma.
Fallopian tube origin for some ovarian carcinomas Diniz PM et al.
Gynaecologic challenging issues in the management of BRCA mutation carriers: oral contraceptives, prophylactic salpingo-oophorectomy and hormone replacement therapy. Gynecol Endocrinol.
In ovarian neoplasms, BRAF, but not KRAS, mutations are restricted to low-grade serous tumours.
Intraepithelial carcinoma of the fimbria and pelvic serous carcinoma: Evidence for a causal relationship.
(2008). Is Chlamydia-infected tubal fimbria the origin of ovarian cancer? Med Hyp.
(2007). Lessons from BRCA: the tubal fimbria emerges as an origin for pelvic serous cancer. Clin Med Res.
(2006). Ovarian cancer and genetic susceptibility in relation to the BRCA1 and BRCA2 genes. Occurrence, clinical importance and intervention. Acta Obstet Gynecol Scand.
Ovarian low-grade and high-grade serous carcinoma: pathogenesis, clinicopathologic and molecular biologic features, and diagnostic problems. Adv Anat Pathol.
Ovarian tumorigenesis: a proposed model based on morphological and molecular genetic analysis.
Patterns of p53 mutations separate ovarian serous borderline tumors and lowand high-grade carcinomas and provide support for a new model of ovarian carcinogenesis: a mutational analysis with immunohistochemical correlation.
(2009). Precursors to pelvic serous carcinoma and their clinical implications. Gynecol Oncol.
Serous tubal intraepithelial carcinoma: its potential role in primary peritoneal serous carcinoma and serous cancer prevention.
(2007). The distal fallopian tube: a new model for pelvic serous carcinogenesis. Curr Opin Obstet Gynecol.
The fallopian tube: primary site of most pelvic high-grade serous carcinomas.
The histologic type and stage distribution of ovarian carcinomas of surface epithelial origin.
The origin and pathogenesis of epithelial ovarian cancer: a proposed unifying theory.
The tubal fimbria is a preferred site for early adenocarcinoma in women with familial ovarian cancer syndrome.
Tumor residual after surgical cytoreduction in prediction of clinical outcome in stage IV epithelial ovarian cancer: a Gynecologic Oncology Group Study.