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IDH1 mutations in a Brazilian series of Glioblastoma

By Miyuki Uno, Sueli Mieko Oba‐Shinjo, Roseli da Silva, Flavio Miura, Carlos Afonso Clara, José Reynaldo Walther de Almeida, Suzana M F Malheiros, André Macedo Bianco, Reynaldo Brandt, Guilherme Carvalhal Ribas, Halim Feres, Carlos Dzik, Sérgio Rosemberg, João Norberto Stavale, Manoel Jacobsen Teixeira and Suely K N Marie
Topics: Rapid Communication
Publisher: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
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Provided by: PubMed Central

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  3. (1994). Astrocytic gliomas: characterization on a molecular genetic basis. Recent Results Cancer Res.
  4. Detection of somatic TP53 splice site mutations in diffuse astrocytomas.
  5. Identification of novel differentially expressed genes in human astrocytomas by cDNA representational difference analysis. Mol Brain Res.
  6. IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas.
  7. IDH1 mutations are present in the majority of common adult gliomas but are rare in primary glioblastomas.
  8. (2009). IDH1 mutations as molecular signature and predictive factor of secondary glioblastomas. Clin Cancer Res.
  9. IDH1 mutations at residue p.R132 (IDH1(R132) occur frequently in high-grade gliomas but not in other solid tumors. Hum Mutat.
  10. (2009). Mutational analysis of IDH1 codon 132 in glioblastomas and other common cancers.
  11. (1985). Probable assignment of soluble isocitrate dehydrogenase (IDH1) to 2q33.3. Hum Genet.
  12. (1999). The human PICD gene encodes a cytoplasmic and peroxisomal NADP(+)-dependent isocitrate dehydrogenase.
  13. The prognostic relevance of molecular alterations in glioblastomas for patients age ,50 years.
  14. (2007). WHO classification of tumours of the central nervous system.