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The role of the microenvironment in tumor immune surveillance

By Oluwadayo Oluwadara, Luca Giacomelli, Xenia Brant, Russell Christensen, Raisa Avezova, George Kossan and Francesco Chiappelli


The evidence appears compelling that the microenvironment, and associated biological cellular and molecular factors, may contribute to the progression of a variety of tumors. The effects of the microenvironment may directly influence the plasticity of T cell lineages, which was recently discussed (O'Shea & Paul, 2010 [4]). To review the putative role of the microenvironment in modulating the commitment of tumor immune surveillance, we use the model of oral premalignant lesions

Topics: Hypothesis
Publisher: Biomedical Informatics
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Provided by: PubMed Central

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