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Spindle Cell Carcinoma of the Tongue: A Rare Tumor in an Unusual Location

By Murat Oktay, Tuba Dilay Kokenek-Unal, Bulent Ocal, Guleser Saylam, Mehmet Hakan Korkmaz and Murat Alper


Spindle cell carcinoma is a rare biphasic tumor consisting of epithelial and mesenchymal components. Presence of this tumor type in the tongue has rarely been reported. Herein, a case of 55-year-old woman who presented with a polypoid lesion at her tongue has been reported. Surgery was performed and pathologic examination revealed a spindle cell carcinoma. We present this rare tumor with an unusual location to contribute in part to the better understanding and awareness of this rare malignancy

Topics: Case Report
Publisher: SAGE-Hindawi Access to Research
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Provided by: PubMed Central

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  1. (2008). A spindle cell carcinoma presenting with osseous metaplasia in the gingiva: a case report with immunohistochemical analysis,”
  2. (1998). Atypical squamous cell carcinoma of the larynx and hypopharynx: radiologic features and pathologic correlation,”
  3. (2008). Cadherin-catenin complex and transcription factor
  4. (2010). Cytology of head and neck squamous cell carcinoma variants,”
  5. (2005). E.B.StelowandS.E.Mills,“Squamouscellcarcinomavariants of the upper aerodigestive tract,”
  6. Fine needle aspiration cytology of spindle cell carcinoma of the tongue: a case report with emphasis on the diagnostic difficulties,”
  7. (2000). i n g h ,J .P .K a n o t r a ,D .L u t h r a ,G .S i n g h ,a n dS .K o t w a l , “Sarcomatoid carcinoma of larynx,”
  8. M.TakagiandG.Ishikawa,“Spindle-cell carcinomaoftheoral cavity,” The Bulletin of
  9. (2009). Morphogenesis and biological significance of spindle cell transformation in a spindle cell carcinoma,”Cancer Letters,
  10. (2007). o, “Evidence-based radiation oncology in head and neck squamous cell carcinoma,”
  11. (2005). Radiotherapy for oral cancer as a risk factor for second primary cancers,”
  12. (2010). Roma˜ n a c h ,R .S .A z e v e d o ,R .C a r l o s ,O .P .D eA l m e i d a
  13. (2006). S i l v e s t r i ,R .L .C a r r a u ,R .P e e l ,a n dJ .L .H u n t ,“ S p i n d l e cellcarcinomaofthelarynxwithactinomyceschondritisofthe larynx and trachea,” Otolaryngology—Head and Neck Surgery,
  14. (1999). S.K u b ot a,T .M orit a,K .M u raka wae tal. ,“ Ac aseorp se u d osar -coma associated with type 3 squamous cell carcinoma of the esophagus: report of a case,” Surgery Today,v o l .2 9 ,n o .8 ,p p .
  15. (2010). Sarcomatoid (spindle cell) carcinoma ofthe head and neck mucosalregion: a clinicopathologic review of 103 cases from a tertiary referral cancercentre,” Headand NeckPathology,vol.4,no.4,pp. 265– 275,
  16. (1981). Sarcomatoid squamous cell carcinoma of the mucous membranes of the head and neck: a clinicopathologic study of 20 cases,”
  17. (2002). Spindle cell (sarcomatoid)carcinomasof the larynx: a clinicopathologic study of 187 cases,”
  18. (2008). Spindle cell carcinoma as a locally recurrent malignancy after surgery for early lingual squamous cell carcinoma,”
  19. (2007). Spindle cell carcinoma of head and neck: an immunohistochemical and molecular approach to its pathogenesis,”
  20. (1997). Spindle cell carcinoma of the larynx and hypopharynx,”
  21. (1997). Spindle cell carcinoma of the larynx: review of 26 cases including DNA content and immunohistochemistry,”
  22. (2006). Spindle cell carcinoma of the oral cavity and oropharynx: factor affecting outcome,”
  23. (1980). Spindle cell carcinoma of the oral cavity.Aclinicopathologicassessmentoffifty-ninecases,”Oral Surgery Oral Medicine and Oral Pathology,v o l .5 0 ,n o .6 ,p p .
  24. (2008). Spindle cell carcinoma of the palatine tonsil: report of a diagnostic pitfall andliteraturereview,”American
  25. (2006). Spindle cell carcinoma,” in Pathology of the Head and Neck,A .C a r d e s aa n dP
  26. (2005). Spindle cell carcinoma,” in World Health Organisation of Tumors. Pathology and Geneticsof Head and Neck
  27. (2008). Spindle cell lesions-neoplastic or nonneoplastic?: spindle cell carcinoma and other atypical spindle cell lesions of the head and neck,”
  28. (2006). Spindle cell sarcoma of larynx,”
  29. (2002). Squamous cell carcinoma of the upper aerodigestive tract: precursors and problematic variants,”
  30. (2005). T1N0 laryngeal sarcomatoidcarcinomathatshowedrapidsystemicmetastases after radical radiotherapy: a case report and review of literature,”
  31. (1995). Treatment of cancer of the head and neck,”