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The costs of human Campylobacter infections and sequelae in the Netherlands: A DALY and cost-of-illness approach

By M.J.J. Mangen, A.H. Havelaar, R.A.J.A.M. Bernsen, G.A. van Koningsveld and G.A. de Wit

Abstract

Campylobacter infections and sequelae pose an important public health problem for the Netherlands. With the help of a second order stochastic simulation model (using @Risk), confidence intervals (CI) for the associated disease burden (summing up morbidity and mortality) and the associated costs-of-illness were estimated. Approximately 80,000 persons per year (90% CI 30,000¿160,000) are estimated to experience symptoms of acute gastro-enteritis, of which 30 are fatal cases. Around 18,000 patients visit a doctor and 500 are hospitalized each year. Additionally, each year some 1,400 cases of reactive arthritis, 59 cases of Guillain-Barré syndrome and 10 cases of inflammatory bowel disease are associated with a previous Campylobacter infection. The disease burden is expressed in Disability Adjusted Life Years (DALYs) and was estimated at 1,200 DALYs (90% CI 900¿1,600 DALYs) per year. The associated costs for the Dutch society, using cost estimates for the year 2000, included direct health-care costs, direct non-health-care costs and productivity losses from missed work and were estimated to total ¿21 million (90% CI ¿11 million ¿¿36 million) per year

Year: 2007
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Provided by: NARCIS
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