This paper explores critical and constructivist theories of technology, and discusses the political and ideological nature of (bio)technology development. The importance of a conceptualization of technologies as value-laden `socio-technical ensembles¿ is discussed, rather than as value-neutral objects, or tools. These conceptualizations are then used to sketch a continuum of development approaches which extends from their relation to a `transfer of technology approach¿, to an `endogenous technology development approach¿. This continuum inspires a rethinking of the possibilities to reconstruct biotechnologies and to tailor them to processes of endogenous development. In doing so, the value of participatory methodologies in coming to a contextualized biotechnology development is re-evaluated
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