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The role of proteomics in depression research

By Daniel Martins-de-Souza, Laura W. Harris, Paul C. Guest, Christoph W. Turck and Sabine Bahn


Depression is a severe neuropsychiatric disorder affecting approximately 10% of the world population. Despite this, the molecular mechanisms underlying the disorder are still not understood. Novel technologies such as proteomic-based platforms are beginning to offer new insights into this devastating illness, beyond those provided by the standard targeted methodologies. Here, we will show the potential of proteome analyses as a tool to elucidate the pathophysiological mechanisms of depression as well as the discovery of potential diagnostic, therapeutic and disease course biomarkers

Topics: Original Paper
Publisher: Springer-Verlag
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Provided by: PubMed Central

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