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Plakophilin 2 Couples Actomyosin Remodeling to Desmosomal Plaque Assembly via RhoA

By Lisa M. Godsel, Adi D. Dubash, Amanda E. Bass-Zubek, Evangeline V. Amargo, Jodi L. Klessner, Ryan P. Hobbs, Xinyu Chen and Kathleen J. Green

Abstract

The desmosomal armadillo protein plakophilin 2 (PKP2) regulates cell contact-initiated cortical actin remodeling through the regulation of RhoA localization and activity to couple adherens junction maturation with desmosomal plaque assembly

Topics: Articles
Publisher: The American Society for Cell Biology
OAI identifier: oai:pubmedcentral.nih.gov:2921118
Provided by: PubMed Central
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