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Quantitative Analysis of a Urine-Based Assay for Detection of Lipoarabinomannan in Patients with Tuberculosis▿

By Maunank Shah, Neil A. Martinson, Richard E. Chaisson, Desmond J. Martin, Ebrahim Variava and Susan E. Dorman


Urinary lipoarabinomannan (LAM) detection is a promising approach for rapid diagnosis of active tuberculosis (TB). In microbiologically confirmed TB patients, quantitative LAM detection results increased progressively with bacillary burden and immunosuppression. Patients with disseminated TB and/or advanced HIV are target populations for whom urine LAM detection may be particularly useful

Topics: Mycobacteriology and Aerobic Actinomycetes
Publisher: American Society for Microbiology (ASM)
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Provided by: PubMed Central
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