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In Vitro Activity of Azithromycin against Nontyphoidal Salmonella enterica▿

By Marianne Gunell, Pirkko Kotilainen, Jari Jalava, Pentti Huovinen, Anja Siitonen and Antti J. Hakanen


The in vitro activity of azithromycin against 1,237 nontyphoidal Salmonella enterica isolates collected from Finnish patients between 2003 and 2008 was investigated. Only 24 (1.9%) of the isolates tested and 15 (5.1%) of the 294 isolates with reduced fluoroquinolone susceptibility had azithromycin MICs of ≥32 μg/ml. These data show that azithromycin has good in vitro activity against nontyphoidal S. enterica, and thus, it may be a good candidate for clinical treatment studies of salmonellosis

Topics: Susceptibility
Publisher: American Society for Microbiology (ASM)
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Provided by: PubMed Central
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