Article thumbnail

Loss of the SIN3 transcriptional corepressor results in aberrant mitochondrial function

By Valerie L Barnes, Bethany S Strunk, Icksoo Lee, Maik Hüttemann and Lori A Pile
Topics: Research Article
Publisher: BioMed Central
OAI identifier: oai:pubmedcentral.nih.gov:2909972
Provided by: PubMed Central

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.

Suggested articles

Citations

  1. (2001). (eds): Molecular Cloning- A Laboratory Manual. Third edition.
  2. (2009). A hyperfused mitochondrial state achieved at G1-S regulates cyclin E buildup and entry into S phase. Proc Natl Acad Sci USA
  3. (2009). A systematic screen for transcriptional regulators of the yeast cell cycle. Genetics
  4. (2007). Alziari S: Aging impact on biochemical activities and gene expression of Drosophila melanogaster mitochondria. Biochimie
  5. (1997). Bessman SP: Hexokinase binding to mitochondria: a basis for proliferative energy metabolism.
  6. (2009). CB: ATP-citrate lyase links cellular metabolism to histone acetylation. Science
  7. (2001). CG: Animal mitochondrial biogenesis and function: a regulatory cross-talk between two genomes. Gene
  8. (2001). Chandrasekaran K: ATP synthesis is coupled to rat liver mitochondrial RNA synthesis. Mol Cell Biochem
  9. (2000). Chromosomal localization links the SIN3-RPD3 complex to the regulation of chromatin condensation, histone acetylation and gene expression. Embo J
  10. (2002). Daynes RA: Nuclear receptor peroxisome proliferatoractivated receptor alpha (PPARalpha) is expressed in resting murine lymphocytes. The PPARalpha in T and B lymphocytes is both transactivation and transrepression competent.
  11. (1997). DE: Histone deacetylase activity is required for full transcriptional repression by mSin3A. Cell
  12. (2006). Dissecting the biological functions of Drosophila histone deacetylases by RNA interference and transcriptional profiling.
  13. (1990). DJ: The Saccharomyces cerevisiae SIN3 gene, a negative regulator of HO, contains four paired amphipathic helix motifs. Mol Cell Biol
  14. (2002). Dufau ML: Silencing of transcription of the human luteinizing hormone receptor gene by histone deacetylase-mSin3A complex.
  15. (2004). Dynlacht BD: A common set of gene regulatory networks links metabolism and growth inhibition. Mol Cell
  16. (2002). Dynlacht BD: E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex. Genes Dev
  17. (2007). Dynlacht BD: E2F-associated chromatin modifiers and cell cycle control. Current opinion in cell biology
  18. (1997). Eisenman RN: Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression. Cell
  19. (2008). Eisenman RN: Myc's broad reach. Genes Dev
  20. (2005). Ekwall K: Sin3: a flexible regulator of global gene expression and genome stability. Current genetics
  21. (2000). Functional discovery via a compendium of expression profiles. Cell
  22. (2002). Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell
  23. (2009). Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae. Genome Biol
  24. (2003). Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network. Genes Dev
  25. (2001). GL: FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity. Genes Dev
  26. (1998). GM: A genetic screen to identify components of the sina signaling pathway in Drosophila eye development. Genetics
  27. (2000). Grigliatti TA: Mutational analysis of a histone deacetylase in Drosophila melanogaster: missense mutations suppress gene silencing associated with position effect variegation. Genetics
  28. (2003). H: Functional characterization of cis- and transregulatory elements involved in expression of phospholipid hydroperoxide glutathione peroxidase. Nucleic Acids Res
  29. (2008). H: Identification of novel modulators of mitochondrial function by a genome-wide RNAi screen in Drosophila melanogaster. Genome Res
  30. (2003). Hockenbery D: c-MYC apoptotic function is mediated by NRF-1 target genes. Genes Dev
  31. (2003). Hockenbery D: Myc's mastery of mitochondrial mischief. Cell cycle (Georgetown, Tex)
  32. (2005). Huttemann M: cAMP-dependent tyrosine phosphorylation of subunit I inhibits cytochrome c oxidase activity.
  33. (2003). Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell
  34. (2004). Korach KS: Estradiol regulates the thioredoxin antioxidant system in the mouse uterus. Endocrinology
  35. (2005). KT: Individual histone deacetylases in Drosophila modulate transcription of distinct genes. Genomics
  36. (2008). LA: Drosophila SIN3 is required at multiple stages of development. Dev Dyn
  37. (2002). Nuclear activators and coactivators in mammalian mitochondrial biogenesis. Biochim Biophys Acta
  38. (2008). Nuclear control of respiratory chain expression by nuclear respiratory factors and PGC-1-related coactivator.
  39. (2006). PA: Prevalence of off-target effects in Drosophila RNA interference screens. Nature
  40. (2004). Peroxisome proliferator-activated receptor alpha target genes. Cell Mol Life Sci
  41. (1993). RA: Stationary phase in the yeast Saccharomyces cerevisiae. Microbiol Rev
  42. (2010). Recovery of DNA Sequences Flanking Pelement Insertions: Inverse PCR and Plasmid Rescue. In Drosophila Protocols Edited by: Sullivan
  43. (1992). Regulation of Carbon and Phosphate Utilization. The Molecular and Cellular Biology of the Yeast Saccharojyces: Gene expression
  44. (1999). Regulation of mammalian O2 homeostasis by hypoxiainducible factor 1. Annu Rev Cell Dev Biol
  45. (1997). Reinberg D: Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex. Cell
  46. (1991). RF: RPD3 encodes a second factor required to achieve maximum positive and negative transcriptional states in Saccharomyces cerevisiae. Mol Cell Biol
  47. (1995). RN: Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3. Cell
  48. (1989). Scarpulla RC: Interaction of nuclear factors with multiple sites in the somatic cytochrome c promoter. Characterization of upstream NRF-1, ATF, and intron Sp1 recognition sequences.
  49. (2008). Sin3B: an essential regulator of chromatin modifications at E2F target promoters during cell cycle withdrawal. Cell cycle (Georgetown, Tex)
  50. (2000). SL: Genomewide studies of histone deacetylase function in yeast.
  51. (2003). Spiegelman BM: Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha: transcriptional coactivator and metabolic regulator. Endocr Rev
  52. (2002). Systematic screen for human disease genes in yeast. Nat Genet
  53. (2005). Systematic screening of nuclear encoded proteins involved in the splicing metabolism of group II introns in yeast mitochondria. Gene
  54. (1961). The Crabtree effect: a review. Cancer Res
  55. (1998). The Drosophila Sin3 gene encodes a widely distributed transcription factor essential for embryonic viability. Development genes and evolution
  56. (2003). The SIN3 deacetylase complex represses genes encoding mitochondrial proteins: implications for the regulation of energy metabolism.
  57. (2002). The SIN3/RPD3 deacetylase complex is essential for G(2) phase cell cycle progression and regulation of SMRTER corepressor levels. Mol Cell Biol
  58. (1996). The synthesis of mRNA in isolated mitochondria can be maintained for several hours and is inhibited by high levels of ATP.
  59. (2001). Tsukiyama T: Widespread collaboration of Isw2 and Sin3-Rpd3 chromatin remodeling complexes in transcriptional repression. Mol Cell Biol
  60. (2008). Tumor necrosis factor alpha inhibits oxidative phosphorylation through tyrosine phosphorylation at subunit I of cytochrome c oxidase.