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Maintenance of HCV-specific T-cell responses in antibody-deficient patients a decade after early therapy

By N. Semmo, M. Lucas, G. Krashias, G. Lauer, H. Chapel and P. Klenerman

Abstract

Early therapy for hepatitis C virus (HCV) is associated with a high rate of viral clearance, but the long-term effects on immune responses remain controversial. The role of antibodies, both acutely and in the long term, is not clearly defined. We investigated these issues in a unique cohort of 7 individuals with primary antibody failure, who had received early interferon therapy after infection through contaminated immunoglobulin therapy a decade previously

Publisher: American Society of Hematology
Year: 2006
OAI identifier: oai:researchrepository.murdoch.edu.au:37144
Provided by: Research Repository
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