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A robust cell cycle control mechanism limits E2F-induced proliferation of terminally differentiated cells in vivo

By Laura A. Buttitta, Alexia J. Katzaroff and Bruce A. Edgar

Abstract

Overexpression of both CycE and E2F is necessary to trigger cell cycle reentry and overproliferation of terminally differentiated wing cells

Topics: Research Articles
Publisher: The Rockefeller University Press
OAI identifier: oai:pubmedcentral.nih.gov:2886355
Provided by: PubMed Central

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Citations

  1. (2007). dE2F2-independent rescue of proliferation in cells lacking an activator dE2F1.
  2. (2007). Differentiated horizontal interneurons clonally expand to form metastatic retinoblastoma in mice.
  3. (2009). MafB/c-Maf deficiency enables self-renewal of differentiated functional macrophages.
  4. (2006). Prospero acts as a binary switch between self-renewal and differentiation in Drosophila neural stem cells.