Article thumbnail

The gene transformer-2 of Anastrepha fruit flies (Diptera, Tephritidae) and its evolution in insects

By Francesca Sarno, María F Ruiz, José M Eirín-López, André LP Perondini, Denise Selivon and Lucas Sánchez
Topics: Research article
Publisher: BioMed Central
OAI identifier:
Provided by: PubMed Central

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.

Suggested articles


  1. (1980). A simple method for estimating evolutionary rate of base substitutions through comparative studies of nucleotide sequences.
  2. (2004). A: The evolution of the Drosophila sex determination pathway. Genetics
  3. (1990). Alternatively spliced transcripts of the sex determining gene tra-2 of Drosophila encode functional proteins of different size.
  4. (1999). BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT. Nucl Acids Symp Ser
  5. (1996). Bootstrap method of interior-branch test for phylogenetic trees. Mol Biol Evol
  6. (1990). BS: Alternative splicing of the sex determination gene transformer-2 is sex-specific in the germ line but not in the soma. Genes Dev
  7. (1991). BS: Autoregulation of the splicing of transcripts from the transformer-2 gene of Drosophila. Genes Dev
  8. (1989). BS: Drosophila doublesex gene controls somatic sexual differentiation by producing alternatively spliced mRNAs encoding related sex-specific polypeptides. Cell
  9. (1991). BS: Regulation of doublesex pre-mRNA processing occurs by 3'-splice site activation. Genes Dev
  10. (1998). Carthew RW: Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway. Cell
  11. (2009). Ceratitis capitata transformer-2 gene is required to establish and maintain the autoregulation of Cctra, the master gene for female sex determination.
  12. (1991). Cline TW: Positive autoregulation of Sexlethal by alternative splicing maintains the female determined state in Drosophila. Cell
  13. (1988). Cline TW: Sex-lethal, a Drosophila sex determination switch gene, exhibits sex-specific RNA splicing and sequence similar to RNA binding proteins. Cell
  14. (2006). Concentration dependent selection of targets by an SR splicing regulator results in tissue-specific RNA processing. Nucl Acids Res
  15. (1985). Confidence limits on phylogenies: an approach using the bootstrap. Evolution
  16. (1991). Control of doublesex alternative splicing by transformer and transformer-2 in Drosophila. Science
  17. (2009). DnaSP v5: a software for comprehensive analysis of DNA polymorphism data. Bioinformatics
  18. (1998). Dübendorfer A: The male-determining activity on the Y chromosome of the housefly (Musca domestica L.) consists of separable elements. Genetics
  19. (2010). Effect of the gene transformer of Anastrepha on the somatic sexual development of Drosophila.
  20. (1992). Elson-Harris MM: Fruit flies of economic significance: their identification and bionomics.
  21. (2008). Gene discovery in an invasive tephritid model pest species, the Mediterranean fruit fly, Ceratitis capitata.
  22. (1985). GG: Cytogenetic mapping of the male-determining region of Lucilia cuprina (Diptera: Calliphoridae). Chromosoma
  23. Hernández-Ortiz V: Phylogeny of the genera Anastrepha and Toxotrypana (Trypetinae: Toxotrypanini) based on morphology. In Fruit Flies (Tephritidae): phylogeny and evolution of behaviour Edited by: Aluja M, Norrbom AL. Boca Ratón:
  24. (2009). Hertel KJ: The SR protein family. Genome Biology
  25. (1996). Identification of the sex-determining region of the Ceratitis capitata Y chromosome by deletion mapping. Genetics
  26. (1995). Interior-branch and bootstrap tests of phylogenetic trees. Mol Biol Evol
  27. (2005). Isolation and characterization of the Bactrocera oleae genes orthologous to the sex determining Sex-lethal and doublesex genes of Drosophila melanogaster. Gene
  28. (2005). JS: A genetic-morphological characterization of two cryptic species of Anastrepha fraterculus complex (Dipetra, Tephritidae). Ann Entomol Soc Amer
  29. (2007). L: The gene doublesex of Anastrepha fruit flies (Diptera, tephritidae) and its evolution in insects. Dev Genes Evol
  30. (2004). L: The gene Sex-lethal of the Sciaridae family (Order Diptera, Suborder Nematocera) and its phylogeny in dipteran insects. Genetics
  31. (1998). LC: The Ceratitis capitata homologue of the Drosophila sex-determining gene Sex-lethal is structurally conserved, but not sex-specifically regulated. Development
  32. (2008). Masculinization of XX Drosophila transgenic flies expressing the Ceratitis capitata DoublsexM isoform.
  33. (2000). McVean GAT: Neutral evolution of the sex-determining gene transformer in Drosophila. Genetics
  34. (2003). Mechanisms of alternative pre-messenger RNA splicing. Annu Rev Biochem
  35. (2006). MF: Cytological characterization of sex chromosomes and ribosomal DNA location in Anastrepha species (Diptera, Tephritidae). Cytogenet Genome Res
  36. (2010). Molecular characterization of the key switch F provides a basis for understanding the rapid divergence of the sex-determining pathway in the housefly. Genetics
  37. (1982). Molecular cloning.
  38. (2000). Molecular Evolution and Phylogenetics.
  39. (1995). Moving up the hierarchy: a hypothesis on the evolution of a genetic sex determination pathway. BioEssays
  40. (1993). MR: The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA.
  41. (2002). Musca domestica, a window on the evolution of sex-determining mechanisms in insects.
  42. (1967). Palenzona D: Response to selection for high number of heterochromosomes
  43. (2005). Perondini ALP, Rocha LS: The mitotic chromosomes of eight species of Anastrepha (Diptera, Tephritidae). Neotrop Entomol
  44. (1997). Perondini ALP: Evaluation of techniques for C and ASG banding of the mitotic chromosomes of Anastrepha fraterculus complex
  45. (2004). Perondini ALP: New variant forms in the Anastrepha fraterculus complex (Diptera, Tephritidae).
  46. (1998). Positive Darwinian selection after gene duplication in primate ribonuclease genes.
  47. (1987). Regulation of sexual differentiation in Drosophila melanogaster via alternative splicing of RNA from the transformer gene. Cell
  48. (2003). RS: Rapid evolution of the sexdetermining gene, transformer: Structural diversity and rate heterogeneity among sibling species of Drosophila. Mol Biol Evol
  49. (2007). S: MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. Mol Biol Evol
  50. (2005). Sánchez L: The gene doublesex of the fruit fly Anastrepha obliqua (Diptera, Tephritidae). Genetics
  51. (2007). Sánchez L: The gene transformer of Anastrepha fruit flies (Diptera, Tephritidae) and its evolution in insects. PLoS ONE
  52. Sex determination and the development of the genital disc.
  53. (2008). Sex-determining mechanisms in insects.
  54. (1964). Sex-limited inheritance and abnormal sex ratio does not contribute to the X:A ratio in strains of the housefly. Genetics
  55. (1991). Sex-specific splicing and polyadenylation of dsx pre-mRNA requires a sequence that binds specifically to tra-2 protein in vitro. Cell
  56. (1982). Spradling AC: Genetic transformation of Drosophila with transposable element vectors. Science
  57. (1993). T: A splicing enhancer complex controls alternative splicing of doublesex pre-mRNA. Cell
  58. (1996). T: Structural and functional conserevation of the Drosophila doublesex splicing enhancer repeat elements. RNA
  59. (2007). The doublesex splicing enhancer components Tra and RBP1 also repress splicing through an intronic silencer. Mol Cell Biol
  60. (1998). The female-determining gene F of the housefly, Musca domestica, acts maternally to regulate its own zygotic activity. Genetics
  61. (1989). The molecular genetics of transformer, a genetic switch-controlling sexual differentiation in Drosophila. Devel Genet
  62. (1987). The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol Biol Evol
  63. (2007). The transformer gene in Bactrocera oleae: the genetic switch that determines its sex fate. Insect Mol Biol
  64. (2002). The transformer gene in Ceratitis capitata provides a genetic basis for selecting and remembering the sexual fate. Development
  65. (2005). The transformer2 gene in Musca domestica is required for selecting and maintaining the female pathway of development. Dev Genes Evol
  66. (1994). TJ: CLUSTAL W: improving the sensitivity of progressive multiple sequence alignments through sequence weighting, position specific gap penalties and weight matrix choice. Nucl Acids Res
  67. (1996). W: A human homologue of the Drosophila sex determination factor transformer-2 has conserved splicing regulatory functions.
  68. (1998). W: Autoregulation of transformer-2 alternative splicing is necessary for normal male fertility in Drosophila. Genetics