Article thumbnail

Expression and activity profiles of DPP IV/CD26 and NEP/CD10 glycoproteins in the human renal cancer are tumor-type dependent

By Adolfo Varona, Lorena Blanco, Itxaro Perez, Javier Gil, Jon Irazusta, José I López, M Luz Candenas, Francisco M Pinto and Gorka Larrinaga
Topics: Research Article
Publisher: BioMed Central
OAI identifier:
Provided by: PubMed Central

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.

Suggested articles


  1. (2008). A: Acid, basic and neutral peptidases present different profiles in chromophobe renal cell carcinoma and in oncocytoma.
  2. (2007). Agirregoitia E, Varona A: Cystinyl aminopeptidase activity is decreased in renal cell carcinomas. Regul Pept
  3. (1999). AN: A role for dipeptidyl peptidase IV in suppressing the malignant phenotype of melanocytic cells.
  4. (2007). and more: interactions that regulate PTEN.
  5. (1990). Animal models and renal carcinogenesis. In Tumors and tumorlike conditions of the kidneys and ureters Edited by: Eble JN.
  6. (1984). BP: A highly sensitive fluorimetric assay for "enkephalinase", a neutral metalloendopeptidase that releases Tyr-GlyGly from enkephalins. Anal Biochem
  7. (2002). C: TNM Classification of Malignant Tumors. 6th edition.
  8. (2004). Candenas ML: mRNA expression of tachykinins and tachykinin receptors in different human tissues.
  9. (2007). Cardillo MR: Quantitative immunohistochemical analysis of matrilysin 1 (MMP-7) in various renal cell carcinoma subtypes.
  10. (2000). Corless CL: Use of antibodies to RCC and CD10 in the differential diagnosis of Renal Neoplasms. Am J Surg Pathol
  11. (2004). Dang NH: CD26/dipeptidyl peptidase IV and its role in cancer. Histol Histopathol
  12. (2008). Dang NH: The role of CD26/dipeptidyl peptidase IV in cancer. Front Biosci
  13. (2000). de La Cadena MP: Preoperative serum CD26 levels: diagnostic efficiency and predictive value for colorectal cancer.
  14. (2002). De Paepe A, Speleman F: Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol
  15. (2006). Diamandis EP: Prognostic implications of the immunohistochemical expression of human kallikreins 5, 6, 10 and 11 in renal cell carcinoma. Tumour Biol
  16. (1998). Endopeptidase 24.11/CD10 is down-regulated in renal cell cancer.
  17. (2004). F: CD10 is expressed in a subset of chromophobe renal cell carcinomas. Mod Pathol
  18. (2005). Fibroblast interaction protein-α and dipeptidyl peptidase IV (CD26): Cell-surface proteases that activate cell signalling and are potential targets for cancer therapy. Drug Resist Updat
  19. (2003). FM: Tachykinins and tachykinin receptors in human uterus.
  20. (2005). Gruaz-Guyon A: A labeled Neutral Endopeptidase Inhibitor as a potential tool for tumor diagnosis and prognosis. Angew Chem Int Ed
  21. (1990). Iris L: Expression of the human nephron differentiation molecules in renal cell carcinomas.
  22. (2007). K: In search of suitable reference genes for gene expression studies of human renal cell carcinoma by real-time PCR. BMC Mol Biol
  23. (2007). Larrinaga G: Altered levels of acid, basic, and neutral peptidase activity and expression in human clear cell renal cell carcinoma.
  24. (2005). Magi-Galluzzi C: The usefulness of immunohistochemical markers in the differential diagnosis of renal neoplasms. Clin Lab Med
  25. (2005). Nanus D: Involvement of neutral endopeptidase in neoplastic progression. Biochim Biophys Acta
  26. (2006). Nanus DM: Neprilysin inhibits angiogenesis via proteolysis of fibroblast growth factor-2.
  27. (1998). Nanus DM: Neutral endopeptidase 24.11 loss in metastatic human prostate cancer contributes to androgen-independent progression. Nat Med
  28. (2004). Nitsche A: Guideline to reference gene selection for quantitative real-time PCR. Biochem Biophys Res Commun
  29. (2005). PF: Representative aminopeptidases and prolyl endopeptidase from murine macrophages: comparative activity levels in resident and elicited cells. Biochem Pharmacol
  30. (1995). PJ: Progesterone-induced secretion of dypeptidyl peptidase-IV (cluster differentiation antigen-26) by the uterine endometrium of the ewe and cow that costimulates lymphocyte proliferation. Endocrinology
  31. (1982). Prognostic significance of morphologic parameters in renal cell carcinoma.
  32. (2006). Röcken C: Ectopeptidases in tumour biology: A review. Histol Histopathol
  33. (2005). S: Dipeptidyl peptidase IV in tumor progression. Biochim Biophys Acta
  34. (2004). Sedo A: Dipeptidyl peptidase IV activity and/or structure homologues (DASH) and their substrates in cancer.
  35. (1995). SF: A novel form of dipeptidylpeptidase IV found in human serum.
  36. (2008). Simoes e Silva AC: Recent advances in the angiotensin-converting enzyme 2-angiotensin (1-7)-Mas axis. Exp Physiol
  37. (2003). Skaletsky H: Primer3 on the WWW for general users and for biologist programmers. Methods Mol Biol
  38. (2004). Transmembrane proteases in cell growth and invasion: new contributors to angiogenesis? Oncogene
  39. (2006). WH: Increasing expression of extracellular matrix metalloprotease inducer in renal cell carcinoma: tissue microarray analysis of immunostaining score with clinicopathological parameters.
  40. (2004). WHO classification of the renal tumors of the adults. Eur Urol
  41. (2004). Zigeuner R: CD10 is a diagnostic and prognostic marker in renal malignancies. Histopathology