(2001). 17 beta-estradiol inhibits cytokine, chemokine, and chemokine receptor mRNA expression in the central nervous system of female mice with experimental autoimmune encephalomyelitis.
(2000). AF: Immunocytochemical evidence for a progesterone receptor in neurons and glial cells of the rat spinal cord. Neurosci Lett
(2005). Angela Sortino M: 17beta-estradiol rescues spinal motoneurons from AMPAinduced toxicity: a role for glial cells. Neurobiol Dis
(1996). Bioavailability of orally administered sex steroids used in oral contraception and hormone replacement therapy. Contraception
(2004). Cutting edge: estrogen drives expansion of the CD4+CD25+ regulatory T cell compartment.
(2006). Estrogen-mediated immunomodulation involves reduced activation of effector T cells, potentiation of Treg cells, and enhanced expression of the PD-1 costimulatory pathway.
(2009). European Charcot Foundation Lecture: the natural history of multiple sclerosis and gender.
(2008). GPR30 contributes to estrogen-induced thymic atrophy. Mol Endocrinol
(2005). Gustafsson JA: Reflections on the discovery and significance of estrogen receptor beta. Endocr Rev
(2008). H: Immunoregulatory factors in multiple sclerosis patients during and after pregnancy: relevance of natural killer cells. Clin Exp Immunol
(2003). H: Oral feeding with ethinyl estradiol suppresses and treats experimental autoimmune encephalomyelitis in SJL mice and inhibits the recruitment of inflammatory cells into the central nervous system.
(1998). Kuchroo VK: IL-10 is critical in the regulation of autoimmune encephalomyelitis as demonstrated by studies of IL-10- and IL-4-deficient and transgenic mice.
(2009). Leeb-Lundberg LM: GPR30/GPER1: searching for a role in estrogen physiology. Trends Endocrinol Metab
(2001). Low-dose estrogen therapy ameliorates experimental autoimmune encephalomyelitis in two different inbred mouse strains.
(2009). Membrane estrogen receptor regulates experimental autoimmune encephalomyelitis through up-regulation of programmed death 1. J Immunol
(1998). Rate of pregnancy-related relapse in multiple sclerosis. Pregnancy in Multiple Sclerosis Group.
RR: Th1 and Th17 cells: adversaries and collaborators.
(1993). Smithies O: Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene. Proc Natl Acad Sci USA
(2008). Steroid hormone receptor expression and function in microglia. Glia
(2007). The complex role of estrogens in inflammation. Endocr Rev
(2003). The protective effect of 17beta-estradiol on experimental autoimmune encephalomyelitis is mediated through estrogen receptor-alpha.
(2007). Treg suppressive activity involves estrogen-dependent expression of programmed death-1 (PD-1). Int Immunol