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Pd/C-mediated synthesis of α-pyrone fused with a five-membered nitrogen heteroaryl ring: A new route to pyrano[4,3-c]pyrazol-4(1H)-ones

By Dhilli Rao Gorja, Venkateswara Rao Batchu, Ashok Ettam and Manojit Pal

Abstract

Pd/C-mediated alkynylation of 5-iodo-pyrazole-4-carboxylic acid, involving the first regioselective construction of α-pyrone ring on a pyrazol moiety via tandem coupling–cyclization process, has been developed to afford pyrano[4,3-c]pyrazol-4(1H)-one in a single pot

Topics: Preliminary Communication
Publisher: Beilstein-Institut
OAI identifier: oai:pubmedcentral.nih.gov:2839514
Provided by: PubMed Central
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