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Structure of single-wall peptide nanotubes: in situ flow aligning X-ray diffraction

By Valeria Castelletto, David R. Nutt, Ian W. Hamley, Seyda Bucak, Celen Cenker and Ulf Olsson

Abstract

The structure of single wall peptide nanotubes is presented for the model surfactant-like peptide A(6)K. Capillary flow alignment of a sample in the nematic phase at high concentration in water leads to oriented X-ray diffraction patterns. Analysis of these, accompanied by molecular dynamics simulations, suggests the favourable self-assembly of antiparallel peptide dimers into beta-sheet ribbons that wrap helically to form the nanotube wall

Topics: Chemical Sciences
Publisher: 'Royal Society of Chemistry (RSC)'
Year: 2010
DOI identifier: 10.1039/c0cc00212g
OAI identifier: oai:lup.lub.lu.se:04015db7-bd9d-4c26-9fc1-34be04ade747
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