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Seroprevalencia de anticuerpos a virus del sarampión, rubeola, parotiditis, hepatitis B y los tres serotipos de poliovirus, en niños de Quindío, Colombia

By María M. González, Luis Sarmiento-Pérez, Alejandra M. Giraldo, Leonardo Padilla, Gloria Rey-Benito and Jhon C. Castaño

Abstract

Objective: The main goal of this research was to assess the seroprevalence of antibodies against measles, rubella, mumps, hepatitis B and all three poliovirus serotypes among children in the Quindio Department, Colombia. Methods: Blood samples were obtained from 170 healthy children aged 5-9 years from nine municipalities in Quindio. The presence of serum IgG antibodies against measles, rubella, mumps and Hepatitis B were determined using commercial indirect ELISA kits. Immunity to poliomyelitis was assessed through the presence of neutralizing antibodies following the method recommended by the World Health Organization. Results: Among the 170 children enrolled, 169 (99.41%), 170(100 %), and 167 (98.2 %) were seropositive to poliovirus 1, poliovirus 2, and poliovirus 3, respectively. The average reciprocal antibody titers were 178 for poliovirus type 1, 120 for type 2 and 56 for type 3. Of the 170 children, 96.47 % were protected against mumps and rubella, and 86.47 % against measles. Only 106 (62.35 %) of the studied subjects were proved to be seropositive to hepatitis B. Conclusion: The immunization program in Quindio has provided seroprotection against all three poliomyelitis serotypes, rubella and mumps. However, the child population is not fully protected against measles and hepatitis B virus infections

Topics: Public Health, Global Health, Social Medicine and Epidemiology, Hepatitis B, Measles, Poliomyelitis, Seroepidemiologic studies, Vaccines
Publisher: 'Universidad Nacional de Colombia'
Year: 2016
DOI identifier: 10.15446/rsap.v18n1.44514
OAI identifier: oai:lup.lub.lu.se:d4c88776-3c3c-4dbf-92bb-a84d518dadaf
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