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The potential advantages of transplanting organs from pig to man: A transplant Surgeon's view

By Carl G. Groth

Abstract

Once pig organs can be transplanted into humans, transplantation will move into a new era. There will be unlimited access to undamaged organs and cells for transplantation and, eventually, donation from deceased or live human beings will become obsolete. Furthermore, it will be possible to alleviate graft rejection, at least in part, by genetic modification of the source animal. Currently, there are three major obstacles to performing transplantations from pig to man: 1) a powerful immune barrier, 2) a potential risk of transmitting microorganisms, particularly endogenous retrovirus and 3) ethical issues related to the future recipients and to society at large

Topics: Symposium
Publisher: Medknow Publications
OAI identifier: oai:pubmedcentral.nih.gov:2721611
Provided by: PubMed Central
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