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Amyloidogenic determinants are usually not buried

By Kimon K Frousios, Vassiliki A Iconomidou, Carolina-Maria Karletidi and Stavros J Hamodrakas
Topics: Research Article
Publisher: BioMed Central
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Provided by: PubMed Central

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  1. (1988). A protein secondary structure prediction scheme for the IBM PC and compatibles.
  2. (2006). A search for amyloidogenic regions in protein chains. Molecular Biology
  3. (2008). Amyloid as a depot for the formulation of long-acting drugs.
  4. (2007). Analysis of chameleon sequences and their implications in biological processes. Proteins: Structure, Function and Bioinformatics
  5. (2000). Assessing the accuracy of prediction algorithms for classification: an overview. Bioinformatics
  6. (2007). Atomic structures of amyloid crossb spines reveal varied steric zippers. Nature
  7. (2005). Cafliesch A: Prediction of aggregation rate and aggregation-prone segments in polypeptide sequences. Protein Science
  8. (2005). CM: Prediction of "aggregation-prone" and "aggregation-susceptible" regions in protein associated with neurodegenerative diseases. Mol Biol
  9. (2006). CM: Protein misfolding, functional amyloid, and human disease. Annu Rev Biochem
  10. (2004). Conformational constraints for amyloid fibrillation: the importance of being unfolded. Biochim Biophys Acta
  11. (1983). Dictionary of protein secondary structure: Pattern recognition of hydrogen-bonded and geometrical features. Biopolymers
  12. (2007). DP: Amyloid peptides and proteins in review. Rev Physiol Biochem Pharmacol
  13. (1974). Fasman GD: Conformational parameters for amino acids in a-helical, b-sheet, and random coil regions calculated from proteins. Biochemistry
  14. (1974). Fasman GD: Prediction of protein conformation. Biochemistry
  15. (2000). Hamodrakas SJ: Amyloids protect the silkmoth oocyte and embryo.
  16. (2008). Hamodrakas SJ: Natural protective amyloids. Curr Prot Pept Sci
  17. (2007). Iconomidou VA: Consensus prediction of amyloidogenic determinants in amyloid-forming proteins.
  18. (2007). Identification of amyloid fibril-forming segments based on structure and residue-based statistical potential. Bioinformatics
  19. (1991). Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr
  20. (2007). JW: Functional amyloidfrom bacteria to humans. Trends Biochem Sci
  21. (2008). Le Béchec A, Delamarche C: AMYPdb: A database dedicated to amyloid precursor proteins.
  22. (2006). Lobanov MV: Prediction of amyloidogenic and disordered regions in protein chains.
  23. (2005). López de la Paz M: The amyloid stretch hypothesis: recruiting proteins toward the dark side. Proc Natl Acad Sci
  24. (2007). On the structural definitions of amyloid fibrils and other polypeptide aggregates Cell. Cell Mol Life Sci
  25. (2000). PE: The Protein Data Bank. Nucleic Acids Research
  26. (2008). PH: We find them here, we find them there: Functional bacterial amyloid. Cell Mol Life Sci
  27. (1999). Protein misfolding, evolution and disease. Trends in Biochem Sci
  28. (2007). S: AGGRESCAN: a server for the prediction and evaluation of "hot spots" of aggregation in polypeptides.
  29. (2006). Seno F: Insight into the structure of amyloid fibrils from the analysis of globular proteins.
  30. (2004). Sequence determinants of amyloid fibril formation. Proc Natl Acad Sci
  31. (2007). Serpell LC: A simple algorithm locates b-strands in the amyloid fibril core of a-synuclein, Áb, and tau using the amino acide sequence alone. Protein Science
  32. (2004). Serrano L: Prediction of sequence-dependent and mutational effects on the aggregation of peptides and proteins. Nature Biotechnology
  33. (2005). Structure of the cross-b spine of amyloid-like fibrils.
  34. (2006). The 3D profile method for identifying fibril-forming segments of proteins. Proc Natl Acad Sci
  35. (2005). The PyMOL molecular graphics system.
  36. (2007). The UniProt Consortium: The Universal Protein Resource (UniProt). Nucleic Acids Res
  37. (2008). Vendruscolo M: Prediction of aggregation-prone regions in structured proteins.
  38. (2004). WJ: Detecting hidden sequence propensity for amyloid fibril formation. Protein Science

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