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Regulation of the Fibrosis and Angiogenesis Promoter SPARC/Osteonectin in Human Adipose Tissue by Weight Change, Leptin, Insulin, and Glucose

By Katrina Kos, Steve Wong, Bee Tan, Anders Gummesson, Margareta Jernas, Niclas Franck, David Kerrigan, Fredrik H. Nystrom, Lena M.S. Carlsson, Harpal S. Randeva, Jonathan H. Pinkney and John P.H. Wilding
Topics: Original Article
Publisher: American Diabetes Association
OAI identifier: oai:pubmedcentral.nih.gov:2712789
Provided by: PubMed Central

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Citations

  1. (1981). a bone-specific protein linking mineral to collagen. Cell
  2. A pericellular collagenase directs the 3-dimensional development of white adipose tissue.
  3. Adenovirusmediated inhibition of SPARC attenuates liver fibrosis in rats.
  4. Adipokines and the insulin resistance syndrome in familial partial lipodystrophy caused by a mutation in lamin A/C.
  5. Alpers CE. Amelioration of diabetic nephropathy in SPARC-null mice.
  6. Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies.
  7. (1998). Correct homeostasis model assessment (HOMA) evaluation uses the computer program. Diabetes Care
  8. Culture of adipose tissue and isolated adipocytes.
  9. (1998). diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med
  10. (1994). Differences in the synthesis of secreted proteins in human retinal endothelial cells of diabetic and nondiabetic origin. Curr Eye Res
  11. Energy restriction lowers the expression of genes linked to inflammation, the cytoskeleton, the extracellular matrix, and angiogenesis in mouse adipose tissue.
  12. Fast Food Study Group. Fast-food-based hyper-alimentation can induce rapid and profound elevation of serum alanine aminotransferase in healthy subjects.
  13. (2003). Identification of differentially expressed genes in models of melanoma progression by cDNA array analysis: SPARC, MIF and a novel cathepsin protease characterize aggressive phenotypes. Exp Dermatol
  14. (2007). Identification of gene signatures for invasive colorectal tumor cells. Cancer Detect Prev
  15. IFATS collection: combinatorial peptides identify alpha5beta1 integrin as a receptor for the matricellular protein SPARC on adipose stromal cells.
  16. (2009). Insulin-induced dephosphorylation of hormoneA
  17. Kra ¨f tI ,M u ¨ller-Scholze
  18. (2009). Leptin is essential for the hepatic fibrogenic response to chronic liver injury.
  19. (2002). Lo ¨n nL ,L o ¨nroth H, Sjo ¨stro ¨m
  20. Metabolic dysregulation and adipose tissue fibrosis: the role of collagen VI.
  21. rather than tumor-produced SPARC, determines stroma and collagen type IV deposition in mammary carcinoma.
  22. Regulation of secreted protein acidic and rich in cysteine during adipose conversion and adipose tissue hyperplasia.
  23. (2002). Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acid Res
  24. Sche ´le E, Gripeteg L, Sjo ¨holm K, Lystig TC, Sjo ¨stro ¨m
  25. Secreted protein acidic and rich in cysteine deficiency ameliorates renal inflammation and fibrosis in angiotensin hypertension.
  26. Separation of human adipocytes by size: hypertrophic fat cells display distinct gene expression.
  27. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.
  28. (1998). SPARC (BM-40, osteonectin) inhibits the mitogenic effect of vascular endothelial growth factor on microvascular endothelial cells.
  29. (1996). SPARC and the extracellular matrix: implications for cancer and wound repair. Curr Top Microbiol Immunol
  30. SPARC inhibits adipogenesis by its enhancement of -catenin signaling.
  31. SPARC-induced increase in glioma matrix and decrease in vascularity are associated with reduced VEGF expression and secretion.
  32. SPARC-null mice display abnormalities in the dermis characterized by decreased collagen fibril diameter and reduced tensile strength.
  33. SPARC-null mice exhibit accelerated cutaneous wound closure.
  34. SPARC-null mice exhibit increased adiposity without significant differences in overall body weight.
  35. (2001). The expression of SPARC in adipose tissue and its increased plasma concentration in patients with coronary artery disease. Obes Res
  36. The matricellular protein SPARC/osteonectin as a newly identified factor up-regulated in obesity.
  37. The proinflammatory cytokine macrophage migration inhibitory factor regulates glucose metabolism during systemic inflammation.
  38. (2008). The role of the matricellular protein SPARC in the dynamic interaction between the tumor and the host. Cancer Metastasis Rev
  39. (2005). Wnt signaling inhibits adipogenesis through beta-catenin-dependent and -independent mechanisms.

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